Investigating the Role of Brain Signals in Working Memory

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study explores how different types of brain stimulation affect working memory performance. Participants will undergo two sessions: the first involves recording brain activity while performing a working memory task, and the second involves receiving various forms of transcranial random aperiodic stimulation (tRAS) while performing the same task. The study aims to determine whether the slope of the aperiodic signal in the brain is more influential on working memory capacity than traditional low-frequency oscillations. The design is double-blinded to ensure unbiased results.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Between the ages of 18 and 35
* Able to provide informed consent
* Normal or corrected-to-normal vision
* Willing to comply with all study procedures and be available for the duration of the study
* Ability to speak, read and understand English without a translator
* Not color-blind

Exclusion Criteria:

* ADHD/ADD (currently under treatment)
* Neurological disorder and conditions
* Medical or neurological illness or treatment for a medical disorder that could interfere with study participation, e.g., unstable cardiac disease, HIV/AIDS, malignancy, liver or renal impairment
* Prior brain surgery
* Any brain devices/implants, including cochlear implants and aneurysm clips
* History of traumatic brain injury
* (For females) Pregnant
* Anything that, in the opinion of the investigator, would place the participant at increased risk or preclude the participant's full compliance with or completion of the study
* Current use of medications know to produce specific EEG activity known to disrupt interpretations of the findings including but not limited to: benzodiazepines, antipsychotics, antiepileptics and central nervous system stimulants

Where it's running

• Florida State University
  Tallahassee, Florida, United States Recruiting

Study contacts

• Principal investigator: Justin Riddle, PhD — Florida State University
• Study coordinator: Justin Riddle, PhD
• Email: jriddle@fsu.edu
• Phone: 850-645-2389

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.