Condition

Coronary Microvascular Dysfunction (CMD) clinical trials and research

• 8Clinical trials
• 8Countries

Newest Coronary Microvascular Dysfunction (CMD) clinical trials

All recruiting trials (8)

• Women with chest pain and non-obstructive arteries: personalized diagnostic and treatment approach

  This study tests a personalized diagnostic-and-treatment pathway for women with angina but non-obstructive coronary arteries to see if targeted therapy improves symptoms and quality of life.

  Recruiting Hospital de Clínicas Dr. Manuel Quintela · Montevideo, Montevideo Department · NCT07593157

• Multi-sensor wireless pressure catheter to test microvascular function in people with angina and non-obstructive arteries

  Doctors are testing a new wireless pressure catheter to see if it can accurately diagnose coronary microvascular dysfunction in people with angina but non-obstructive arteries, using MRI perfusion as the reference test.

  Recruiting at 2 sites Peking University Third Hospital · Beijing, Beijing Municipality and 4 other locations · NCT07453381

• How kidney transplant affects blood flow in the heart's tiny vessels in people with advanced CKD

  This study will try to see if getting a kidney transplant improves blood flow in the small vessels of the heart for people with advanced chronic kidney disease who are on the transplant waitlist.

  Recruiting Brigham and Women's Hospital · Boston, Massachusetts · NCT07222683

• Nitrate Beetroot Juice to Help Blood Flow in Women with ANOCA and CMD

  We’re testing whether nitrate-rich beetroot juice for 14 days can improve heart blood flow and quality of life for women with ANOCA and CMD compared with a placebo.

  Recruiting University of Virginia · Charlottesville, Virginia · NCT06948201

• Personalized exercise and dietary program for patients with microvascular coronary dysfunction

  This study is testing a personalized exercise and diet program to see if it helps people with microvascular coronary dysfunction feel better and manage their symptoms.

  Recruiting at 2 sites Royal United Hospitals Bath NHS Foundation Trust · Bath and 1 other locations · NCT06681896

• Improving heart blood flow and angina in women using an SGLT2 pill (STRONG)

  This trial will test whether taking the SGLT2 pill Brezavvy for 12 weeks can improve coronary microvascular blood flow and reduce angina symptoms in women with non-obstructive coronary artery disease.

  Recruiting Phase 1 University of Virginia · Charlottesville, Virginia · NCT06600178

• Registry for patients with non-obstructive coronary artery disease

  This study looks at people with non-obstructive coronary artery disease to see how common chest pain is and if personalized treatments can improve their symptoms and overall health over five years.

  Recruiting Federico II University · Naples, Italy · NCT06588244

• Stratified medicine approach for managing angina without obstructive coronary artery disease

  This study is testing if a personalized treatment plan based on a special heart test can help people with angina who don’t have blocked arteries feel better and improve their health.

  Recruiting at 30 sites NHS Greater Glasgow and Clyde · Cork and 38 other locations · NCT04674449

Related topics

Quick answers

How many Coronary Microvascular Dysfunction (CMD) clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 8 countries. The most sites are in United States (3 trials), United Kingdom (2 trials), Ireland (1 trial), Netherlands (1 trial), Poland (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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