Condition

Caffeine clinical trials and research

• 8Clinical trials
• 1New in 30 days
• 6Countries

Newest Caffeine clinical trials

All recruiting trials (8)

• Morning-strength boost with caffeine or whole-body vibration

  This study tests whether taking 300 mg caffeine or using whole-body vibration helps healthy, regularly trained adults see improvements in morning strength and thinking skills.

  Recruiting Phase 4 Liverpool John Moores University · Liverpool, Merseyside · NCT07921810

• How external factors affect 2D-NIRS tissue oxygenation measurements in healthy volunteers

  This study tests how things like temperature, activity, caffeine, and nicotine influence 2D-NIRS measurements of tissue oxygenation in healthy adults.

  Recruiting Heinrich-Heine University, Duesseldorf · Düsseldorf · NCT07854431

• Does caffeine help professional chess players think faster and play better?

  In this study, professional chess players try caffeinated versus decaffeinated coffee to see if caffeine improves focus, reaction time, and game performance.

  Recruiting St. Louis University · St Louis, Missouri · NCT07641335

• Does Caffeine or Alcohol Change Pupil Reactions? A Test in Healthy Adults

  This study tests how caffeine and alcohol affect pupil responses and eye movements, and whether these changes can indicate recent intake, in adults aged 30-50.

  Recruiting National University of Singapore · Singapore · NCT07625358

• Sublingual caffeine to shorten recovery and reduce agitation after general anesthesia in older adults

  This trial will test whether a single dose of sublingual caffeine helps people aged 65 and older wake up faster and have less postoperative agitation after elective eye surgery under general anesthesia.

  Recruiting Cairo University · Cairo · NCT07536568

• Impact of Caffeine on the Blood Stem Cells in Healthy Adults

  This study tests whether a single 200 mg dose of caffeine changes blood stem and progenitor cells in healthy adults who regularly drink caffeine compared with those who rarely or never do.

  Recruiting ETH Zurich · Zurich, Canton of Zurich and 1 other locations · NCT07193264

• Effects of caffeine on learning in healthy adults using brain imaging

  This study tests how caffeine affects learning and brain activity in healthy adults by comparing its effects to a placebo during tasks that involve rewards.

  Recruiting Phase 4 Martinos Center for Biomedical Imaging · Charlestown, Massachusetts · NCT06763172

• Personalized caffeine dosing for better performance during sleep deprivation

  This study is testing if a personalized caffeine plan can help people perform better and feel less tired after not getting enough sleep.

  Recruiting at 2 sites University of Arizona · Tucson, Arizona and 1 other locations · NCT05588934

Related topics

Quick answers

How many Caffeine clinical trials are recruiting right now?

8, as of November 12, 2026. 1 of them was first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 6 countries. The most sites are in United States (3 trials), Singapore (1 trial), United Kingdom (1 trial), Germany (1 trial), Egypt (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 4: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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