How external factors affect 2D-NIRS tissue oxygenation measurements in healthy volunteers

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, single-center study uses 2D-NIRS imaging to map regional tissue oxygenation in healthy volunteers and to see how external conditions and everyday behaviors alter the readings. It employs a controlled design to evaluate factors such as ambient temperature, temporary vascular occlusion, physical activity, caffeine, and nicotine intake. The goal is to develop a standardized measurement protocol to improve reliability for future research and for assessing microvascular perfusion in patients with critical illness. The project is physiological and methodological, not designed to test a therapy or provide direct benefit to participants.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy volunteers aged 20-40 years
* Written informed consent
* Ability to understand and comply with the study procedures

Exclusion Criteria:

* Age below 20 years or above 40 years
* Cardiovascular disease or other relevant medical conditions
* current medication, where relevant to the study procedures
* contraindication to or inability to undergo the planned examinations
* Any condition that may interfere with the study procedures or outcome measurements

Where it's running

• University Hospital Duesseldorf
  Düsseldorf, Germany Recruiting

Study contacts

• Study coordinator: Patricia Wischmann, MD
• Email: patricia.wischmann@med.uni-duesseldorf.de
• Phone: +49211 18000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.