Condition

Appendicitis clinical trials and research

• 9Clinical trials
• 15Countries

Newest Appendicitis clinical trials

All recruiting trials (9)

• How PEG bowel preparation affects gut bacteria in people with or without an appendix

  This observational study will test whether polyethylene glycol colonoscopy prep changes gut bacteria differently in adults who have had an appendectomy compared with those who have not.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT07478029

• Closing the appendix stump with clips versus ties during laparoscopic appendectomy

  This study tests whether using metal clips or tying sutures to close the appendix stump during laparoscopic appendectomy leads to fewer complications and lower costs for people with acute appendicitis.

  Recruiting Sohag University · Sohag · NCT07115303

• Global assessment of appendicitis management outcomes

  This study looks at how appendicitis is treated in hospitals around the world to see if improvements can be made for all patients needing surgery.

  Recruiting at 4 sites University of Birmingham · Cotonou and 6 other locations · NCT06774001

• Using Fitbit to detect infections in children after appendectomy

  This study tests if using Fitbit data can help doctors spot infections early in children recovering from appendix surgery.

  Recruiting at 2 sites Ann & Robert H Lurie Children's Hospital of Chicago · Chicago, Illinois and 3 other locations · NCT06395636

• Comparing Ketorolac and Morphine for Pain Relief in Children with Appendicitis

  This study is testing if ketorolac can help relieve pain just as well as morphine in children aged 6-17 who might have appendicitis.

  Recruiting Phase 3 University of Calgary · Calgary, Alberta · NCT06160778

• Comparing selective imaging methods to routine imaging for suspected appendicitis

  This study is testing if using specific imaging methods based on symptoms can help adults suspected of having appendicitis get better care compared to standard imaging methods.

  Recruiting at 3 sites Helsinki University Central Hospital · Espoo and 2 other locations · NCT06083064

• Same Day Ambulatory Appendectomy

  This study tests whether doing appendectomies on the same day without an overnight hospital stay can safely help people with uncomplicated appendicitis feel better and improve their overall care experience.

  Recruiting at 17 sites Centre Hospitalier Universitaire de Nice · Nice, Alpes Maritimes and 32 other locations · NCT05691348

• Evaluating the impact of peritoneal irrigation during laparoscopic appendectomy for appendicitis

  This study is testing if washing out the abdomen during laparoscopic surgery for appendicitis can help prevent infections in adults with this condition.

  Recruiting Niguarda Hospital · Milan · NCT05075252

• Comparing surgery and non-surgery for complicated appendicitis

  This study is testing whether surgery or non-surgery works better for adults with complicated appendicitis that includes an abscess or phlegmon.

  Recruiting Yale University · New Haven, Connecticut · NCT04168866

Related topics

Quick answers

How many Appendicitis clinical trials are recruiting right now?

9, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 15 countries. The most sites are in United States (2 trials), Canada (1 trial), Italy (1 trial), Egypt (1 trial), France (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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