Global assessment of appendicitis management outcomes
A Global Prospective Cohort Study on Outcomes of Appendicectomy for Appendicitis
This study looks at how appendicitis is treated in hospitals around the world to see if improvements can be made for all patients needing surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 14000 (estimated) |
| Sex | All |
| Sponsor | University of Birmingham Academic / other |
| Locations | 7 sites (Cotonou and 6 other locations) |
| Trial ID | NCT06774001 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate and enhance the management of appendicitis by examining emergency care systems worldwide. It will gather data from hospitals performing appendicectomy over a 14-day period, focusing on key performance measures related to access, quality, and efficiency of surgical care. The study will include all consecutive patients undergoing appendicectomy for suspected or confirmed appendicitis, with no age restrictions. By identifying gaps in emergency surgical care, particularly in low- and middle-income countries, the study seeks to improve patient outcomes and reduce healthcare costs.
Who should consider this trial
Good fit: Ideal candidates include any patients undergoing appendicectomy for suspected or confirmed appendicitis, regardless of age.
Not a fit: Patients who do not undergo appendicectomy or have alternative diagnoses unrelated to appendicitis may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved emergency surgical care for appendicitis, enhancing patient outcomes globally.
How similar studies have performed: Previous cohort studies have shown success in similar approaches, indicating the potential for meaningful insights and improvements.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age: There are no age restrictions, although, if appropriate participating hospitals can choose to only include children or only adults, based on an age cut-off of their choice. * Procedure: All patients undergoing appendicectomy for suspected or confirmed appendicitis by any surgical approach should be included. This includes patients who went theatre with suspect appendicitis even if the intraoperative or pathology results found a different diagnosis, so long as an appendicectomy was performed. It also includes patients who went to theatre for reasons other than suspected appendicitis but were found to have appendicitis intraoperatively and underwent appendicectomy. This includes interval appendicectomy and right hemicolectomy if performed for acute appendicitis. * Approach: Both open and minimally invasive (laparoscopic and robotic) interventions are eligible for inclusion. Laparoscopic and robotic converted to open cases are also eligible. Exclusion Criteria: * Indication: Appendicectomy for any indication other than suspected or confirmed appendicitis should be excluded. For example, patients having appendicectomy for known appendiceal neoplasm. * Procedure: Patients having appendectomy as part of another surgical procedure should be excluded. For example, patients having removal of appendix as part of a colon cancer procedure are not eligible for inclusion. * Approach: Natural orifice surgery and endoscopic treatment for suspected appendicitis are excluded. * Previous appendicectomy: Patients having surgery for stump appendicitis are excluded. * Return to theatre: Patients should be entered into study only once. A patient returning to theatre after appendectomy should not be re-entered as a new patient.
Where this trial is running
Cotonou and 6 other locations
- University of Abomey Calavi — Cotonou, Benin (Not_yet_recruiting)
- Tamale Teaching Hospital — Tamale, Ghana (Recruiting)
- Christian Medical College and Hospital Ludhiana — Ludhiana, India (Not_yet_recruiting)
- Hospital Espanol Veracruz — Veraruz, Mexico (Recruiting)
- Lagos University Teaching Hospital — Lagos, Nigeria (Recruiting)
- University Teaching Hospital of Kigali (CHUK) — Kigali, Rwanda (Not_yet_recruiting)
- Chris Hani Baragwanath Academic Hospital — Johannesburg, South Africa (Recruiting)
Study contacts
- Study coordinator: Teddy Anyomih
- Email: t.t.k.anyomih@bham.ac.uk
- Phone: +441214143344
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.