Global assessment of appendicitis management outcomes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate and enhance the management of appendicitis by examining emergency care systems worldwide. It will gather data from hospitals performing appendicectomy over a 14-day period, focusing on key performance measures related to access, quality, and efficiency of surgical care. The study will include all consecutive patients undergoing appendicectomy for suspected or confirmed appendicitis, with no age restrictions. By identifying gaps in emergency surgical care, particularly in low- and middle-income countries, the study seeks to improve patient outcomes and reduce healthcare costs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age: There are no age restrictions, although, if appropriate participating hospitals can choose to only include children or only adults, based on an age cut-off of their choice.
* Procedure: All patients undergoing appendicectomy for suspected or confirmed appendicitis by any surgical approach should be included. This includes patients who went theatre with suspect appendicitis even if the intraoperative or pathology results found a different diagnosis, so long as an appendicectomy was performed. It also includes patients who went to theatre for reasons other than suspected appendicitis but were found to have appendicitis intraoperatively and underwent appendicectomy. This includes interval appendicectomy and right hemicolectomy if performed for acute appendicitis.
* Approach: Both open and minimally invasive (laparoscopic and robotic) interventions are eligible for inclusion. Laparoscopic and robotic converted to open cases are also eligible.

Exclusion Criteria:

* Indication: Appendicectomy for any indication other than suspected or confirmed appendicitis should be excluded. For example, patients having appendicectomy for known appendiceal neoplasm.
* Procedure: Patients having appendectomy as part of another surgical procedure should be excluded. For example, patients having removal of appendix as part of a colon cancer procedure are not eligible for inclusion.
* Approach: Natural orifice surgery and endoscopic treatment for suspected appendicitis are excluded.
* Previous appendicectomy: Patients having surgery for stump appendicitis are excluded.
* Return to theatre: Patients should be entered into study only once. A patient returning to theatre after appendectomy should not be re-entered as a new patient.

Where it's running

• Tamale Teaching Hospital
  Tamale, Ghana Recruiting
• Hospital Espanol Veracruz
  Veraruz, Mexico Recruiting
• Lagos University Teaching Hospital
  Lagos, Nigeria Recruiting
• Chris Hani Baragwanath Academic Hospital
  Johannesburg, South Africa Recruiting
• University of Abomey Calavi
  Cotonou, Benin Not yet recruiting
• Christian Medical College and Hospital Ludhiana
  Ludhiana, India Not yet recruiting

Study contacts

• Study coordinator: Teddy Anyomih
• Email: t.t.k.anyomih@bham.ac.uk
• Phone: +441214143344

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using Fitbit to detect infections in children after appendectomy

  This study tests if using Fitbit data can help doctors spot infections early in children recovering from appendix surgery.

  Recruiting at 2 sites Ann & Robert H Lurie Children's Hospital of Chicago · Chicago, Illinois and 3 other locations · NCT06395636

• Evaluating the impact of peritoneal irrigation during laparoscopic appendectomy for appendicitis

  This study is testing if washing out the abdomen during laparoscopic surgery for appendicitis can help prevent infections in adults with this condition.

  Recruiting Niguarda Hospital · Milan · NCT05075252

• Video-based grading of intraoperative adverse events during pediatric laparoscopic appendectomy

  This project tests whether using video recordings and ClassIntra can reliably grade intraoperative adverse events in children undergoing laparoscopic appendectomy.

  Recruiting TC Erciyes University · Kayseri, Kayseri · NCT07794618

• Quality of Life and Pain After Appendix Surgery in Children

  This study looks at whether some kids still have pain and lower quality of life three months after an appendix removal.

  Recruiting Kocaeli City Hospital · Kocaeli, İzmit · NCT07629362

• How PEG bowel preparation affects gut bacteria in people with or without an appendix

  This observational study will test whether polyethylene glycol colonoscopy prep changes gut bacteria differently in adults who have had an appendectomy compared with those who have not.

  Recruiting Tongji Hospital · Wuhan, Hubei · NCT07478029

• Intraperitoneal bupivacaine versus saline to reduce pain after open appendectomy

  This will test whether placing bupivacaine into the abdominal cavity during open appendectomy reduces postoperative pain more than saline for adults who come to the emergency department.

  Recruiting Phase 1 Services Institute of Medical Sciences, Pakistan · Lahore, Punjab Province · NCT07429448

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.