Evaluating the impact of peritoneal irrigation during laparoscopic appendectomy for appendicitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective observational multicenter trial aims to assess the effects of laparoscopic lavage during laparoscopic appendectomy on the incidence of postoperative intra-abdominal abscesses in adult patients with acute appendicitis. The study will categorize patients based on the grade of contamination and severity of appendicitis to determine if the use of irrigation offers any advantages over suction alone. By introducing a classification system for different degrees of appendicitis and contamination, the study seeks to clarify the relationship between surgical techniques and postoperative outcomes. Data will be collected preoperatively, intra-operatively, and postoperatively to identify predictive factors for infectious complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients between 18 and 69 years old
* Surgical laparoscopic approach for AA
* Intra-operative and histological diagnosis of AA

Exclusion Criteria:

* Patients \< 18 years old or \> 69 years old
* Previous appendectomy
* Previous appendicitis treated conservatively
* Open approach for surgery or intra-operative conversion
* Co-existence of other intra-abdominal infections (IAI)
* Patients with immunodeficiency
* Patients treated with steroid, immunosuppressant, or CHT within previous 6 months

Where it's running

• ASST GOM Niguarda
  Milan, Italy Recruiting

Study contacts

• Study coordinator: Stefano Pietro Cioffi, MD
• Email: stefanopiero.cioffi@ospedaleniguarda.it
• Phone: +393386032519

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Using Fitbit to detect infections in children after appendectomy

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• Video-based grading of intraoperative adverse events during pediatric laparoscopic appendectomy

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  Recruiting TC Erciyes University · Kayseri, Kayseri · NCT07794618

• Quality of Life and Pain After Appendix Surgery in Children

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• How PEG bowel preparation affects gut bacteria in people with or without an appendix

  This observational study will test whether polyethylene glycol colonoscopy prep changes gut bacteria differently in adults who have had an appendectomy compared with those who have not.

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• Intraperitoneal bupivacaine versus saline to reduce pain after open appendectomy

  This will test whether placing bupivacaine into the abdominal cavity during open appendectomy reduces postoperative pain more than saline for adults who come to the emergency department.

  Recruiting Phase 1 Services Institute of Medical Sciences, Pakistan · Lahore, Punjab Province · NCT07429448

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.