Closing the appendix stump with clips versus ties during laparoscopic appendectomy
Official title: Results of Laparoscopic Appendectomy With Application of Clips Versus Ligature for Stump Closure: A Comparative Study
Run by Sohag University · NCT07115303 · Data updated 2026-11-12
This study tests whether using metal clips or tying sutures to close the appendix stump during laparoscopic appendectomy leads to fewer complications and lower costs for people with acute appendicitis.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Status | Recruiting |
| Started | July 14, 2025 |
| Main results expected | February 28, 2026 |
| Study ends | February 28, 2026 |
| Registry record updated | August 11, 2025 |
| Trial ID | NCT07115303 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are patients of any age or sex presenting to the emergency department with uncomplicated acute appendicitis who are treated at Sohag University Hospital.
✕Probably not a fit
Patients with complicated appendicitis, unstable cardiac or pulmonary problems, or those found to have suspected Crohn's disease or an intraoperative mass are excluded and may not benefit from the findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective comparison of two techniques for closing the appendiceal stump during laparoscopic appendectomy: application of clips versus ligature (tying sutures). Patients of any age or sex who present with uncomplicated acute appendicitis at Sohag University Hospital are enrolled, while those with complicated appendicitis, unstable cardiac or pulmonary conditions, or intraoperative suspicion of Crohn's disease or a mass are excluded. Outcomes include technical feasibility, postoperative complications such as fecal fistula, and economic considerations. Procedures are performed at a single center and data are collected during the perioperative and early postoperative period.
Why it matters
Potential benefit: If successful, the trial could identify a safer and more cost-effective method to close the appendix stump in uncomplicated laparoscopic appendectomy.
How similar studies have gone: Previous surgical series comparing clips, ligatures (endoloops), and staplers for stump closure in uncomplicated appendicitis have shown mixed but generally comparable safety and cost profiles for clips versus ties.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Any patient diagnosed with acute appendicitis of any age and of any sex presented to ER of the Department of General, Laparoscopic and Oncologic Surgery Department, Sohag University Hospital will be enrolled in this study. Exclusion Criteria: * Patients with complicated appendicitis. * Patients with unstable cardiac or pulmonary condition. * Patients with suspicious crhon's disease or mass intraoperative.
Where it's running
-
Sohag university hospital
Sohag, Egypt Recruiting
Study contacts
- Study coordinator: Ahmed A Abdelreheem, Resident
- Email: ahmeddd_amerrr@yahoo.com
- Phone: 01026675749
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.