Condition

Adverse Childhood Experiences clinical trials and research

• 8Clinical trials
• 1Country

Newest Adverse Childhood Experiences clinical trials

All recruiting trials (8)

• How childhood adversity and SIRT1 affect early blood vessel aging.

  This project will test whether taking nicotinamide riboside can boost SIRT1 and improve blood vessel function in 18–30-year-olds with high levels of childhood adversity compared with those with no ACEs.

  Recruiting University of Wisconsin, Madison · Iowa City, Iowa and 1 other locations · NCT07073352

• Teaching healthy regulation to adolescents in challenging environments

  This study is testing a coaching program called GRIT to see if it can help young teens who have faced tough challenges avoid using alcohol and cannabis.

  Recruiting University of California, Irvine · Irvine, California · NCT06821035

• Program to prevent substance use and support families affected by childhood trauma

  This study is testing whether a program that combines family support with community resources can help reduce substance use and the effects of childhood trauma in families across New Jersey.

  Recruiting RTI International · Tinton Falls, New Jersey · NCT06236100

• School shootings and safety measures: effects on student and staff mental health and school engagement

  This project will test whether exposure to school shootings and the safety measures schools use affect mental health, feelings of safety, and academic engagement for middle and high school students and school staff.

  Recruiting Teachers College, Columbia University · New York, New York · NCT06153316

• Effects of exercise on cognition in adults with childhood trauma

  This study is testing whether different types of exercise can help improve thinking skills in middle-aged adults who faced abuse or neglect as children.

  Recruiting University of Texas at Austin · Austin, Texas · NCT05972265

• Exploring how childhood experiences affect smoking risk in young adults

  This study is trying to see how tough childhood experiences affect the brain's response to nicotine in young adults who don't smoke, to understand why they might be at a higher risk of starting to smoke.

  Recruiting Early Phase 1 Duke University · Durham, North Carolina · NCT05665465

• Improving family resilience for children with adverse childhood experiences

  This study is testing a new support program for families with children aged 3 to 11 who have faced tough experiences, to see if it helps improve their health and well-being.

  Recruiting Loma Linda University · Loma Linda, California · NCT05388864

• Early-life exposures and breastfeeding in children with sickle cell disease

  This project will try a community breastfeeding support group for mothers of infants with sickle cell disease to see if breastfeeding and related supports improve early-life exposures and child health.

  Recruiting University of Alabama at Birmingham · Birmingham, Alabama · NCT05377372

Related topics

Quick answers

How many Adverse Childhood Experiences clinical trials are recruiting right now?

8, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

All of them have sites in United States. Each study page lists its sites and which ones are recruiting.

What phases are they in?

Early Phase 1: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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