Effects of exercise on cognition in adults with childhood trauma

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how different types of exercise, both acute and chronic, affect cognitive function in middle-aged adults who have experienced abuse or neglect during childhood. Participants will undergo a series of assessments and exercise interventions over a period of up to 78 days, including neuropsychological testing and symptom measures. The study aims to compare the effects of moderate intensity exercise against a placebo of light intensity exercise to determine the most beneficial approach for improving cognitive complaints.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* between 40 and 60 years of age
* history of child abuse or neglect
* have a complaint about memory, attention, or executive function
* native or fluent English speaker
* normal or corrected to normal vision and hearing
* medically healthy

Exclusion Criteria:

* Score indicating a history of moderate-intensity activity, hard-intensity activity, or very-hard intensity activity on the Stanford Brief Activity Survey
* current excessive alcohol or other substance use
* eating disorder, bipolar disorder, schizophrenia spectrum disorders, or those judged to be an immediate suicide risk based on having an active plan with intent
* autism spectrum disorder, attention-deficit/hyperactivity disorder (ADHD), or other neurodevelopmental disorder
* neurocognitive disorder, or illnesses or history of neurological events known to cause neurocognitive disorders (e.g., traumatic brain injury, status epilepticus, stroke)
* reported chest pain or dizziness during exercise; any endorsed and not controlled medical condition that could make exercise contraindicated, including hypertension; heart disease; heart failure; hear rhythm disorders; heart valve disease; metabolic conditions; chronic obstructive pulmonary disease; pulmonary hypertension; cystic fibrosis; asthma; and bone, joint, or soft tissue problems
* pregnancy, major medical disorders such as cancer, or any other condition believed to put a participant at risk

Where it's running

• University of Texas at Austin
  Austin, Texas, United States Recruiting

Study contacts

• Principal investigator: Erin Logue, PhD — University of Texas at Austin

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.