Effects of exercise on cognition in adults with childhood trauma
Exercise and Cognition in Middle-Aged Adults With Histories of Childhood Trauma and Cognitive Complaints
NA · University of Texas at Austin · NCT05972265
This study is testing whether different types of exercise can help improve thinking skills in middle-aged adults who faced abuse or neglect as children.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 34 (estimated) |
| Ages | 40 Years to 60 Years |
| Sex | All |
| Sponsor | University of Texas at Austin (other) |
| Locations | 1 site (Austin, Texas) |
| Trial ID | NCT05972265 on ClinicalTrials.gov |
What this trial studies
This study investigates how different types of exercise, both acute and chronic, affect cognitive function in middle-aged adults who have experienced abuse or neglect during childhood. Participants will undergo a series of assessments and exercise interventions over a period of up to 78 days, including neuropsychological testing and symptom measures. The study aims to compare the effects of moderate intensity exercise against a placebo of light intensity exercise to determine the most beneficial approach for improving cognitive complaints.
Who should consider this trial
Good fit: Ideal candidates are adults aged 40 to 60 with a history of childhood abuse or neglect and cognitive complaints.
Not a fit: Patients with significant neurocognitive disorders or those currently engaging in high levels of physical activity may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to effective exercise-based interventions that improve cognitive function in adults with a history of childhood trauma.
How similar studies have performed: While there is ongoing research into the effects of exercise on cognitive function, this specific approach targeting adults with childhood trauma is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * between 40 and 60 years of age * history of child abuse or neglect * have a complaint about memory, attention, or executive function * native or fluent English speaker * normal or corrected to normal vision and hearing * medically healthy Exclusion Criteria: * Score indicating a history of moderate-intensity activity, hard-intensity activity, or very-hard intensity activity on the Stanford Brief Activity Survey * current excessive alcohol or other substance use * eating disorder, bipolar disorder, schizophrenia spectrum disorders, or those judged to be an immediate suicide risk based on having an active plan with intent * autism spectrum disorder, attention-deficit/hyperactivity disorder (ADHD), or other neurodevelopmental disorder * neurocognitive disorder, or illnesses or history of neurological events known to cause neurocognitive disorders (e.g., traumatic brain injury, status epilepticus, stroke) * reported chest pain or dizziness during exercise; any endorsed and not controlled medical condition that could make exercise contraindicated, including hypertension; heart disease; heart failure; hear rhythm disorders; heart valve disease; metabolic conditions; chronic obstructive pulmonary disease; pulmonary hypertension; cystic fibrosis; asthma; and bone, joint, or soft tissue problems * pregnancy, major medical disorders such as cancer, or any other condition believed to put a participant at risk
Where this trial is running
Austin, Texas
- University of Texas at Austin — Austin, Texas, United States (RECRUITING)
Study contacts
- Principal investigator: Erin Logue, PhD — University of Texas at Austin
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Adverse Childhood Experiences