Condition

Advanced or Metastatic Solid Tumors clinical trials and research

• 14Clinical trials
• 7Countries

Newest Advanced or Metastatic Solid Tumors clinical trials

All recruiting trials (14)

• SHY-ONC6: a new anti-cancer drug tested in adults with advanced solid tumors

  This early-phase study tests SHY-ONC6 to see if it is safe and can help people with advanced solid tumors after standard therapies have failed.

  Recruiting at 3 sites Phase 1 SHY Therapeutics · Scottsdale, Arizona and 2 other locations · NCT07705334

• Precision-matched donor CAR-NK cell therapy targeting one or two tumor antigens for advanced solid tumors

  This trial tests banked donor CAR‑NK cell infusions matched to the antigens in an adult's tumor to see if they are safe and can shrink advanced solid tumors.

  Recruiting Phase 1/2 Beijing Biotech · Shenzhen, Guangdong · NCT07510828

• KGX101 alone and with envafolimab for advanced or metastatic solid tumors

  This trial will test whether KGX101 by itself or combined with envafolimab is safe and tolerable for adults in China with advanced or metastatic solid tumors.

  Recruiting at 3 sites Phase 1 Kangabio AUSTRALIA LTD PTY · Beijing, Beijing Municipality and 2 other locations · NCT07260305

• TAK-188 for adults with advanced or metastatic solid tumors

  This trial will test whether TAK-188, a drug that targets CCR8 to remove immune-suppressing cells in tumors, helps adults with advanced or metastatic solid tumors whose cancer has not improved after prior treatments.

  Recruiting at 15 sites Phase 1/2 Takeda · Santa Monica, California and 14 other locations · NCT07205718

• Testing LNCB74 in patients with advanced solid tumors

  This study is testing a new treatment called LNCB74 to see if it's safe and how well it works for people with advanced solid tumors like ovarian, breast, and lung cancer.

  Recruiting at 14 sites Phase 1 LigaChem Biosciences, Inc. · Newport Beach, California and 16 other locations · NCT06774963

• Evaluating a new treatment for advanced or metastatic solid tumors

  This study is testing a new treatment for people with advanced or metastatic solid tumors to see if it is safe and effective after they have tried other therapies.

  Recruiting at 11 sites Phase 1 Day One Biopharmaceuticals, Inc. · New Haven, Connecticut and 10 other locations · NCT06752681

• Testing HM16390 for advanced or metastatic solid tumors

  This study is testing a new treatment called HM16390 for people with advanced or metastatic solid tumors who haven't had success with other therapies to see if it can help them.

  Recruiting at 7 sites Phase 1 Hanmi Pharmaceutical Company Limited · Los Angeles, California and 7 other locations · NCT06724016

• Testing a new drug ETX-19477 for advanced solid tumors

  This study is testing a new drug called ETX-19477 to see if it can help people with advanced solid tumors that haven't responded to other treatments.

  Recruiting at 14 sites Phase 1/2 858 Therapeutics, Inc. · Phoenix, Arizona and 13 other locations · NCT06395519

• Evaluating TGI-6 for advanced solid tumors

  This study is testing a new treatment called TGI-6 to see if it is safe and effective for people with advanced solid tumors, especially those with colorectal cancer.

  Recruiting Phase 1 Hefei TG ImmunoPharma Co., Ltd. · Beijing · NCT06374173

• Testing KK2260 in patients with advanced or metastatic solid tumors

  This study is testing a new drug called KK2260 to see if it is safe and effective for people with advanced or metastatic solid tumors.

  Recruiting at 14 sites Phase 1 Kyowa Kirin Co., Ltd. · Nagoya, Aichi-ken and 13 other locations · NCT06248411

• Testing BH3120 alone or with pembrolizumab for advanced solid tumors

  This study is testing a new treatment called BH3120, both alone and with another drug called pembrolizumab, to see if it can help people with advanced solid tumors.

  Recruiting at 9 sites Phase 1 Hanmi Pharmaceutical Company Limited · Tampa, Florida and 9 other locations · NCT06234397

• Safety and blood levels of PMC-309, an anti‑VISTA antibody, in adults with advanced solid tumors

  This will test PMC-309, alone or with pembrolizumab, in adults with advanced solid tumors that have progressed after prior treatments to see if it is safe and how it behaves in the body.

  Recruiting at 4 sites Phase 1 PharmAbcine · Benowa, Queensland and 3 other locations · NCT05957081

• Testing DCSZ11 for advanced or metastatic solid tumors

  This study is testing a new treatment called DCSZ11, alone and with another drug, to see if it helps people with advanced or metastatic solid tumors.

  Recruiting at 29 sites Phase 1 DynamiCure Biotechnology · Birmingham, Alabama and 34 other locations · NCT05785754

• New CAR T cell therapy for advanced solid tumors

  This study is testing a new CAR T cell therapy for people with advanced solid tumors to see if it can help fight their cancer better.

  Recruiting Phase 1/2 Chinese PLA General Hospital · Beijing, Beijing Municipality · NCT05693844

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Quick answers

How many Advanced or Metastatic Solid Tumors clinical trials are recruiting right now?

14, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 7 countries. The most sites are in United States (8 trials), China (4 trials), South Korea (3 trials), Australia (2 trials), Japan (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 10, Phase 1/2: 4. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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