Condition

Acute Lymphocytic Leukemia clinical trials and research

• 13Clinical trials
• 9Countries

Newest Acute Lymphocytic Leukemia clinical trials

All recruiting trials (13)

• BCOR and ZC3H12 gene‑knockout CD19 CAR‑T therapy for adults with relapsed/refractory B‑cell ALL

  This will test whether autologous CD19‑targeting CAR‑T cells with BCOR and ZC3H12 genes knocked out can be safe and produce durable remissions in adults with relapsed or refractory B‑cell acute lymphoblastic leukemia.

  Recruiting Phase 1/2 Chinese PLA General Hospital · Beijing, Biotherapeutic Department of Chinese PLA General Hospital and 1 other locations · NCT07008885

• Combining an unmodified family (haplo‑identical) donor graft with cord blood for transplant

  This trial will test whether giving an unmodified haplo‑identical donor graft followed by a cord blood graft with post‑transplant cyclophosphamide helps people with high‑risk AML, ALL, or MDS stay free of disease.

  Recruiting Phase 2 Case Comprehensive Cancer Center · Cleveland, Ohio · NCT06904482

• New CAR-T therapy with IL-15 for treating blood cancers

  This study is testing a new CAR-T therapy combined with IL-15 to see if it can help people with blood cancers like leukemia and multiple myeloma.

  Recruiting Shanxi Bethune Hospital · Taiyuan, Shanxi · NCT06783816

• Gene Knock-out CAR-T Cell Therapy for Acute Lymphocytic Leukemia

  This study is testing a new type of CAR-T cell therapy to see if it can help people with hard-to-treat B-cell acute lymphoblastic leukemia feel better and fight their cancer.

  Recruiting at 5 sites Phase 1/2 Chinese PLA General Hospital · Beijing, Beijing Municipality and 5 other locations · NCT06481735

• Study of crushed venetoclax tablets dissolved in liquid for pediatric patients

  This study tests if crushing venetoclax tablets and mixing them with liquid helps children with blood cancers absorb the medication better and stay safe while taking it.

  Recruiting at 5 sites Children's Hospital Medical Center, Cincinnati · Aurora, Colorado and 5 other locations · NCT06131801

• Stem cell transplant using a specific preparative regimen for blood cancers

  This study is testing a new way to prepare for a stem cell transplant using a special combination of medications and radiation to see if it helps people with acute leukemia who are in remission.

  Recruiting Phase 2 Masonic Cancer Center, University of Minnesota · Minneapolis, Minnesota · NCT05805605

• New CAR T-cell therapy for children and young adults with certain blood cancers

  This study is testing a new CAR T-cell therapy that uses modified cells from children's and young adults' own blood to see if it can help treat certain tough-to-treat blood cancers.

  Recruiting Phase 1/2 National Institutes of Health Clinical Center (CC) · Bethesda, Maryland · NCT05442515

• Oral treatment with LP-118 for patients with various blood cancers

  This study is testing a new oral treatment called LP-118 to see if it is safe and can help people with certain types of blood cancers that have come back or didn’t respond to other treatments.

  Recruiting at 8 sites Phase 1 Newave Pharmaceutical Inc · Chicago, Illinois and 7 other locations · NCT04771572

• Using ponatinib to treat children with advanced leukemias, lymphomas, or solid tumors

  This study is testing if ponatinib can help children with hard-to-treat leukemias, lymphomas, or solid tumors feel better and have more treatment options.

  Recruiting at 22 sites Phase 1/2 Incyte Corporation · Ghent and 22 other locations · NCT03934372

• Imaging study to evaluate leukemia treatment response

  This study is testing if a special type of imaging can help doctors see how well treatments are working for people with high-risk acute leukemia or myeloma.

  Recruiting Phase 1 University of Oklahoma · Washington D.C., District of Columbia and 2 other locations · NCT03633955

• Using Inotuzumab Ozogamicin after Stem Cell Transplant for Acute Lymphocytic Leukemia

  This study is testing if a new drug called inotuzumab ozogamicin can help people with acute lymphocytic leukemia who have had a stem cell transplant stay healthy and avoid relapse.

  Recruiting at 4 sites Phase 1/2 Case Comprehensive Cancer Center · Westwood, Kansas and 6 other locations · NCT03104491

• Collecting and reporting data on patients receiving stem cell transplants

  This study is trying to gather and share information about patients getting stem cell transplants for blood cancers to better understand how well these treatments work.

  Recruiting Wake Forest University Health Sciences · Winston-Salem, North Carolina · NCT01890486

• Using modified T-cells to treat advanced B-cell cancers

  This study is testing whether modified T-cells can help patients with advanced B-cell cancers that haven't responded to other treatments by boosting their immune system to fight the cancer better.

  Recruiting at 2 sites Phase 1 Baylor College of Medicine · Houston, Texas and 1 other locations · NCT01853631

Related topics

Quick answers

How many Acute Lymphocytic Leukemia clinical trials are recruiting right now?

13, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 9 countries. The most sites are in United States (9 trials), China (3 trials), Belgium (1 trial), France (1 trial), Italy (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1/2: 5, Phase 1: 3, Phase 2: 2. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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