Condition
Acute Appendicitis clinical trials and research
As of November 12, 2026, Find a Trial lists 8 Acute Appendicitis clinical trials that are recruiting, at sites in 5 countries (most in Turkey (Türkiye) (4), Italy (1), Poland (1)). 2 were first registered in the last 30 days. By phase: Phase 4 (1). Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 8Clinical trials
- 2New in 30 days
- 5Countries
Newest Acute Appendicitis clinical trials
| Study | Phase | Where | Status | Registered |
|---|---|---|---|---|
| Inflammatory biomarkers in blood and appendix tissue in acute appendicitis | — | Istanbul, Istanbul | Recruiting | Nov 9, 2026 |
| Test of Pro-Adrenomedullin for diagnosing acute appendicitis in adults | — | Bursa | Recruiting | Oct 22, 2026 |
| Pediatric ERAS-Adapted Laparoscopic Appendectomy Feasibility | — | Kayseri, Kayseri | Recruiting | Jun 11, 2026 |
| Comparing CT scan reports and the AIR score in adults having an appendectomy for suspected appendicitis. | — | Sanliurfa, Şanlıurfa | Recruiting | Mar 27, 2026 |
| Urinary PGE-M to help predict acute appendicitis in children | — | Split | Recruiting | Jun 6, 2025 |
| Using AI to train doctors in pediatric care | — | Guiyang, Guizhou and 2 other locations | Recruiting | Nov 21, 2024 |
| Using magnesium sulfate to reduce opioid use in children having laparoscopic appendectomy | Phase 4 | Warsaw | Recruiting | Aug 20, 2024 |
| International registry for emergency surgery and trauma | — | Pisa | Recruiting | Aug 23, 2018 |
All recruiting trials (8)
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Inflammatory biomarkers in blood and appendix tissue in acute appendicitis
This study tests whether blood and appendix tissue biomarkers correlate with how severe a patient’s acute appendicitis is, to help distinguish uncomplicated from complicated cases.
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Test of Pro-Adrenomedullin for diagnosing acute appendicitis in adults
We are testing whether Pro-Adrenomedullin can help diagnose acute appendicitis in adults and how it compares to CRP and NLR.
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Pediatric ERAS-Adapted Laparoscopic Appendectomy Feasibility
This study tests a 20-item enhanced recovery protocol in children aged 5–18 undergoing laparoscopic appendectomy to see if it can be safely and reliably applied in a real clinical setting.
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Comparing CT scan reports and the AIR score in adults having an appendectomy for suspected appendicitis.
This will try to see if CT scan reports and the Appendicitis Inflammatory Response (AIR) score can accurately identify true appendicitis in adults who have an appendectomy after a CT suggests appendicitis.
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Urinary PGE-M to help predict acute appendicitis in children
We will test whether a urine marker called PGE-M can help diagnose acute appendicitis in children ages 5 to 17 who come in with sudden belly pain.
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Using AI to train doctors in pediatric care
This study is testing whether using virtual patients powered by AI can help train doctors in China to better care for children with common health issues.
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Using magnesium sulfate to reduce opioid use in children having laparoscopic appendectomy
This study tests if giving magnesium sulfate through an IV can help reduce the amount of opioids kids need during laparoscopic appendectomy surgery.
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International registry for emergency surgery and trauma
This study is setting up a worldwide registry for emergency surgeries and trauma cases to help doctors track their results and find better ways to treat patients.
Related topics
Quick answers
How many Acute Appendicitis clinical trials are recruiting right now?
8, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 5 countries. The most sites are in Turkey (Türkiye) (4 trials), Italy (1 trial), Poland (1 trial), Croatia (1 trial), China (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 4: 1. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.