Using magnesium sulfate to reduce opioid use in children having laparoscopic appendectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of intravenous magnesium sulfate infusion as a co-analgesic in children undergoing laparoscopic appendectomy. It aims to assess its impact on opioid consumption and the physiological responses to anesthesia and surgical trauma. The study follows a multimodal approach to anesthesia, combining different methods and medications to minimize opioid use. The primary outcome is the measurement of opioid consumption during the procedure, while secondary outcomes include various intraoperative responses.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* ASA (American Society of Anesthesiologists) physical status class 1E, 2E, 3E (E - emergency)
* Patients undergoing laparoscopic appendectomy

Exclusion Criteria:

* Allergy to the magnesium sulfate or the excipient
* Hypermagnesemia
* Renal failure (GFR \<30 ml/min)
* Myasthenia gravis
* Preoperative atrioventricular block
* Hypotension
* The use of digitalis glycosides
* The use of oral anticoagulants
* ASA physical status class 4E or higher
* Chronic treatment with analgesics
* Legal guardians or patient refusal

Where it's running

• Uniwersity Clinic Centre of Medical Uniwersity of Warsaw
  Warsaw, Poland Recruiting

Study contacts

• Study coordinator: Alicja Kuczerowska, MD
• Email: alicja.kuczerowska@uckwum.pl
• Phone: 601666694

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.