V132 vaccine safety in healthy older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This Phase 1 trial evaluates multiple formulations of the V132 vaccine in healthy adults aged older than 60. Participants receive one of several V132 formulations or comparator vaccines to monitor safety and immune responses. The study excludes individuals with recent pneumococcal disease or prior pneumococcal vaccines within specified timeframes. Sites are located in California and Florida, enrolling participants in a controlled clinical setting with routine follow-up visits. Data will inform whether V132 can safely provoke an immune response in this population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

The key inclusion criteria include but are not limited to the following:

* Is in good health
* Has body mass index (BMI) within 18.0 to 35.0 kg/m\^2 (inclusive)

Exclusion Criteria:

The key exclusion criteria include but are not limited to the following:

* Has a history of invasive pneumococcal disease or known history of other culture-positive pneumococcal disease within 3 years prior to receiving study vaccination
* Has received a pneumococcal polysaccharide vaccine in the previous 10 years, has received any pneumococcal conjugate vaccine at any time prior to this study

Where it's running

• Anaheim Clinical Trials ( Site 0006)
  Anaheim, California, United States Recruiting
• Velocity Clinical Research, Hallandale Beach ( Site 0003)
  Hallandale, Florida, United States Recruiting
• Research Centers of America ( Hollywood ) ( Site 0009)
  Hollywood, Florida, United States Recruiting
• QPS-MRA, LLC-Early Phase ( Site 0001)
  South Miami, Florida, United States Recruiting
• Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0002)
  Springfield, Missouri, United States Recruiting
• Velocity Clinical Research Lincoln ( Site 0007)
  Lincoln, Nebraska, United States Recruiting

Study contacts

• Study coordinator: Toll Free Number
• Email: Trialsites@msd.com
• Phone: 1-888-577-8839

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.