Using ultrasound to study nerves and muscles

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to improve the understanding of nerve and muscle health by utilizing advanced ultrasound imaging techniques. Researchers will evaluate healthy adults and those with neuromuscular disorders to gather normative data on muscle and nerve structure and function. Participants will undergo medical history reviews and physical exams during outpatient visits, where various ultrasound modalities will be employed to assess nerve and muscle characteristics. The goal is to identify reliable biomarkers that can enhance clinical evaluations of neuromuscular diseases.

Why it matters

Who can join: the full rules

* INCLUSION CRITERIA:

In order to be eligible to participate in this study, an individual must meet all of the following criteria:

1. Healthy Volunteers-Adults

   1. Healthy adults, male or female, aged 18 years old or older,
   2. In good general health as evidenced by medical history, medical conditions under control such as hypertension acceptable.
   3. Stated willingness to comply with all study procedures and availability for the duration of the study.
   4. Ability of subject to understand and the willingness to sign a written informed consent document.
2. Participants with neuromuscular disorders

   1. Adults, male or female, aged 18 years old or older,
   2. Diagnosed with a neuromuscular disorder or have signs and symptoms of nerve or muscle disorder or neuromuscular diaphragm dysfunction.
   3. Stated willingness to comply with all study procedures and availability for the duration of the study.
   4. Ability of subject to understand and the willingness to sign a written informed consent document.

EXCLUSION CRITERIA:

1. Healthy Volunteers-Adults

   History of stroke, muscle disorders, peripheral neuropathy, or spine surgery
2. Participants with neuromuscular disorders

No clinical evidence of a neuromuscular disorder on clinical evaluation.

Where it's running

• National Institutes of Health Clinical Center
  Bethesda, Maryland, United States Recruiting

Study contacts

• Principal investigator: Tanya J Lehky, M.D. — National Institute of Neurological Disorders and Stroke (NINDS)
• Study coordinator: Candida C Silva
• Email: candida.silva@nih.gov
• Phone: (301) 496-7428

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.