Using QL Block to Reduce Pain After Myomectomy
Quadratus Lumborum Block to Improve Postoperative Pain Management After Laparoscopic Myomectomies: a Double-blinded and Prospective Randomized Clinical Trial.
This study is testing if a special pain relief injection in the lower back can help women feel less pain after surgery to remove uterine fibroids.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | University Hospitals Cleveland Medical Center Academic / other |
| Locations | 1 site (Beachwood, Ohio) |
| Trial ID | NCT05979493 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of a quadratus lumborum (QL) block in reducing postoperative pain for patients undergoing myomectomy to remove uterine fibroids. Participants will be randomly assigned to receive either the QL block along with standard anesthesia and pain management or standard care alone. The QL block involves an anesthetic injection in the lower back muscle, which has shown promise in alleviating pain in similar surgical contexts. The goal is to determine if this approach can enhance pain relief for patients post-surgery.
Who should consider this trial
Good fit: Ideal candidates are women with uterine fibroids requiring surgical excision who are willing to participate in the study.
Not a fit: Patients with pre-existing conditions such as anxiety, depression, chronic pain, or those who are non-English speaking may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce postoperative pain and improve recovery experiences for patients undergoing myomectomy.
How similar studies have performed: Previous studies have shown that QL blocks can effectively reduce postoperative pain in various abdominal and pelvic surgeries, indicating a promising approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Presence of uterine fibroids requiring surgical excision with preservation of the uterus * Stated willingness to comply with all study procedures and availability for the duration of the study * Provision of signed and dated informed consent form Exclusion Criteria: * Pre-existing diagnoses of anxiety or depression * Pre-existing coagulopathies * Pre-existing neuropathic or chronic pelvic pain * Chronic opioid use * Illiteracy due to inability to read and understand plain questionnaire * Non-English speaking * BMI \>38
Where this trial is running
Beachwood, Ohio
- University Hospitals Ahuja Medical Center — Beachwood, Ohio, United States (Recruiting)
Study contacts
- Principal investigator: Joseph Findley, MD — University Hospitals
- Study coordinator: Catherine P Haering, BA
- Email: cph43@case.edu
- Phone: 3392011531
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.