Clinical trial Recruiting at 3 sites Observational Ages 18 to 120

Using PPG to Predict Heart Function in the General Population

Official title: Photoplethysmography (PPG) to Predict Ejection Fraction and Other Echographic Data in the General Population

Run by Tulane University · NCT04843371 · Data updated 2026-11-12

This study is testing if a wristband can help predict heart function in adults by comparing its readings with traditional heart scans.

Quick facts

Study typeObservational
Ages18 Years to 120 Years
SexAll
Enrollment500 (estimated)
SponsorTulane University
Academic / other
Locations3 sites (New Orleans, Louisiana and 2 other locations)
StatusRecruiting
StartedAugust 20, 2021
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedMarch 5, 2026
Trial IDNCT04843371 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18 and older who are scheduled for an echocardiogram at Tulane Medical Center.

Probably not a fit

Patients under 18, those with cognitive impairments, or individuals unable to wear the Biostrap device will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the relationship between ejection fraction (EF) measured by echocardiography and signals obtained from Photoplethysmography (PPG) in individuals aged 18 and older. Participants scheduled for an echocardiogram at Tulane University's outpatient cardiology clinic will have their demographics, health habits, and medical history collected. During the echocardiogram, PPG recordings will be taken simultaneously using a Biostrap wristband. The study seeks to develop a predictive model for estimating ventricular ejection fraction based on PPG signals, potentially offering a non-invasive alternative to traditional echocardiography.

Why it matters

Potential benefit: If successful, this study could provide a non-invasive method for estimating heart function, improving patient access to cardiac assessments.

How similar studies have gone: While the use of PPG in cardiac assessments is emerging, this specific approach to predict ejection fraction is novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male or Female aged18 years or older.
* Patients scheduled to undergo an echocardiogram at Tulane Medical Center.

Exclusion Criteria:

* Participants under 18 years of age.
* Participants with cognitive impairments.
* Participants with a physical inability to wear the Biostrap during the echocardiogram.
* Individuals who cannot read, speak, and/or understand English.

Where it's running

  • East Jefferson General Hospital
    New Orleans, Louisiana, United States
    Recruiting
  • University Medical Center
    New Orleans, Louisiana, United States
    Recruiting
  • Tulane Doctors - Speciality Care - Napoleon
    New Orleans, Louisiana, United States
    Recruiting

Study contacts

  • Principal investigator: Nassir Marrouche, MD — Tulane University
  • Study coordinator: Mayana Bsoul, MD
  • Email: mbsoul@tulane.edu
  • Phone: 504-988-3063

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.