Using Nafamostat for better ECMO management

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates a new approach to managing anticoagulation in patients on ECMO, focusing on the use of Nafamostat combined with low-intensity systemic anticoagulation. ECMO is a life-support technique for patients with severe respiratory or circulatory failure, but it carries a high risk of bleeding and thrombotic events. By optimizing anticoagulation strategies, the study aims to reduce these risks and improve patient outcomes. The trial will include adult patients who have received ECMO due to severe respiratory failure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age older than 18 years old
* received VV ECMO because of severe respiratory failure

Exclusion Criteria:

* anticoagulant contraindications
* cerebral infarction or suspected patients
* severe hypertension
* women in gestational and lactational period
* hemophilia
* allergic to heparin or Nafamostat
* unwilling or unable to complete the study

Where it's running

• Bing Sun
  Beijing, Beijing Municipality, China Recruiting

Study contacts

• Principal investigator: Bing Sun, MD — Beijing Chao Yang Hospital
• Study coordinator: Bing Sun, MD
• Email: ricusunbing@126.com
• Phone: +8613911151075

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.