Super-Early Neuroprognostication in eCPR Patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project investigates whether automated pupillometry and continuous near-infrared spectroscopy (cNIRS) can identify early neurological status in adults evaluated for eCPR. It uses observational methods to analyze neuroprognostic indicators soon after ECMO initiation, aiming to improve selection and timing. The study context emphasizes time-critical decision-making and seeks to establish predictive values for earlier prognosis. Data collection centers on bedside pupillometry and cerebral oxygenation monitoring in the emergency department setting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All patients ≥ 18 years evaluated for eCPR treatment at the Department of Emergency Medicine

Exclusion Criteria:

* Return of spontaneous circulation before ECMO initiation.
* Anatomical infeasibility for measurement, including but not limited to:
* Severe facial trauma or deformity preventing the placement of the automated pupillometry device.
* Scalp injuries, dressings, or conditions that interfere with the correct positioning of near-infrared spectroscopy (NIRS) sensors.
* Pre-existing ocular conditions that preclude reliable pupillometry (e.g., enucleation, opaque cornea, or severe anisocoria unrelated to neurological status).

Where it's running

• Department of Emergency Medicine, Medical University of Vienna
  Vienna, Austria Recruiting

Study contacts

• Study coordinator: Jürgen Grafeender, MD, PhD
• Email: juergen.grafeneder@meduniwien.ac.at
• Phone: +43 1 40400 19540

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.