Using lubrication gel during embryo transfer in IVF
Official title: Lubricant Gel Versus Sterile Water for Speculum Insertion During Embryo Transfer: a Randomized Non-inferiority Clinical Trial
Run by Wolfson Medical Center · NCT06210451 · Data updated 2026-11-12
This study is testing whether using a special lubrication gel during embryo transfer in IVF can help women aged 18-40 have a higher chance of a live birth.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | Women only |
| Enrollment | 416 (estimated) |
| Sponsor | Wolfson Medical Center Government |
| Locations | 1 site (Tel Aviv) |
| Status | Recruiting |
| Started | May 1, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | July 24, 2024 |
| Trial ID | NCT06210451 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are women aged 18-40 undergoing their first to third embryo transfer with fresh or thawed embryos.
✕Probably not a fit
Patients over the age of 40 or those undergoing egg donation cycles may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the impact of using a sterile water-based lubrication gel during the embryo transfer (ET) process in in vitro fertilization (IVF). The study aims to determine whether the gel affects the live birth rate per transfer, addressing concerns that it may hinder ET success. Participants will include women aged 18-40 undergoing their first to third ET with fresh or thawed embryos. The trial will compare outcomes between those who receive the gel and those who do not, contributing to the understanding of best practices in embryo transfer.
Why it matters
Potential benefit: If successful, this study could enhance patient comfort during embryo transfer without compromising the chances of a successful pregnancy.
How similar studies have gone: Previous studies have shown that the use of small amounts of water-soluble gel does not negatively impact cervical cytology, suggesting potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18-40 * Fresh and thawed ET * Patients undergoing their 1st-3rd ET * ET of 1-2 embryos Exclusion Criteria: * Age\>40 * Egg donation cycles
Where it's running
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Faculty of Medical and Health Sciences
Tel Aviv, Israel Recruiting
Study contacts
- Principal investigator: Daniel Tairy, MD — Edith Wolfson Medical Center
- Study coordinator: Daniel Tairy, MD
- Email: danieltairy1@gmail.com
- Phone: +972-54-5315875
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.