Non-invasive embryo genetic screening in egg donation cycles

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, blinded, non-selection study in women receiving donor oocytes who undergo single blastocyst transfer. Embryos will be chosen for transfer using standard morphological criteria only, and the spent culture medium will be collected without influencing clinical decisions. Cell-free embryonic DNA in the spent medium will be analyzed by next-generation sequencing to detect chromosomal aneuploidies (niPGTA). The study will compare niPGTA results from transferred embryos that implant or lead to ongoing pregnancy versus those that fail to implant or result in pregnancy loss.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Women between 18 and 50 years old who are oocyte recipients.
* Signed consent form
* Transfer of a single blastocyst-stage embryo
* Male with normal sperm FISH

Exclusion Criteria:

* Uterine malformations
* Abnormal karyotypes in either partner
* Failure to sign informed consent

Where it's running

• Instituto Bernabeu
  Alicante, Spain Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.