G-CSF for DOR in women undergoing IVF

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, double-blind, placebo-controlled Phase 4 study enrolling 140 women with diminished ovarian reserve (POSEIDON group 4) undergoing IVF. Participants receive either Neupogen G-CSF 300 μg or saline in five injections every other day starting in the early luteal phase, targeting ovarian response. The goal is to determine if G-CSF can improve IVF success metrics in this specific population. The study is conducted at The Center for Human Reproduction in New York, with the lead sponsor overseeing the trial. Safety and efficacy data will inform whether G-CSF could become a therapeutic option for DOR in IVF settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Infertile women aged 35-44 years who have indication to undergo IVF and meet the POSEIDON group 4 (DOR): FSH \<10 IU/L and AMH \>1.2 ng/mL
* Participants will be recruited from patients undergoing IVF treatment at The CHR

Where it's running

• The Center for Human Reproduction
  New York, New York, United States Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.