Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using leftover human tissue from surgeries for research on vascular calcification

Official title: Use of Discarded Surgery Human Tissue Specimens for Basic Science Research

Run by Centre Hospitalier Universitaire, Amiens · NCT04753593 · Data updated 2026-11-12

This study is trying to understand how certain cells contribute to vascular calcification by using leftover tissue from heart and bone surgeries.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment200 (estimated)
SponsorCentre Hospitalier Universitaire, Amiens
Academic / other
Locations1 site (Amiens)
StatusRecruiting
StartedJanuary 4, 2021
Main results expectedJune 2026
Study endsJune 2026
Registry record updatedJune 15, 2026
Trial IDNCT04753593 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients undergoing cardiac or orthopedic surgeries at the CHU Amiens-Picardie who consent to the use of their discarded tissue specimens.

Probably not a fit

Patients who are HIV or hepatitis positive will not benefit from this study as they are excluded from participation.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the processes involved in vascular calcification by utilizing discarded human tissue specimens obtained from patients undergoing cardiac and orthopedic surgeries. The research focuses on understanding the roles of various cell types, including osteoblasts and vascular smooth muscle cells, in the calcification process. By conducting in vitro cell culture experiments with these pseudonymized tissue samples, the study seeks to shed light on the mechanisms of calcification and inform future clinical management strategies for affected patients.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and management of vascular calcification, potentially benefiting patients with related conditions.

How similar studies have gone: While this approach of using discarded tissue for research is not novel, the specific focus on vascular calcification may provide new insights that have not been extensively explored in previous studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing surgery in the Cardiac Surgery and Orthopedic Surgery departments of the CHU Amiens-Picardie
* patients who will be beforehand informed
* patients who will not be opposed to this study.

Exclusion Criteria:

* HIV and hepatitis positive patients

Where it's running

  • CHU Amiens
    Amiens, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.