Using leftover human tissue from surgeries for research on vascular calcification
Official title: Use of Discarded Surgery Human Tissue Specimens for Basic Science Research
Run by Centre Hospitalier Universitaire, Amiens · NCT04753593 · Data updated 2026-11-12
This study is trying to understand how certain cells contribute to vascular calcification by using leftover tissue from heart and bone surgeries.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens) |
| Status | Recruiting |
| Started | January 4, 2021 |
| Main results expected | June 2026 |
| Study ends | June 2026 |
| Registry record updated | June 15, 2026 |
| Trial ID | NCT04753593 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients undergoing cardiac or orthopedic surgeries at the CHU Amiens-Picardie who consent to the use of their discarded tissue specimens.
✕Probably not a fit
Patients who are HIV or hepatitis positive will not benefit from this study as they are excluded from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to investigate the processes involved in vascular calcification by utilizing discarded human tissue specimens obtained from patients undergoing cardiac and orthopedic surgeries. The research focuses on understanding the roles of various cell types, including osteoblasts and vascular smooth muscle cells, in the calcification process. By conducting in vitro cell culture experiments with these pseudonymized tissue samples, the study seeks to shed light on the mechanisms of calcification and inform future clinical management strategies for affected patients.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of vascular calcification, potentially benefiting patients with related conditions.
How similar studies have gone: While this approach of using discarded tissue for research is not novel, the specific focus on vascular calcification may provide new insights that have not been extensively explored in previous studies.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing surgery in the Cardiac Surgery and Orthopedic Surgery departments of the CHU Amiens-Picardie * patients who will be beforehand informed * patients who will not be opposed to this study. Exclusion Criteria: * HIV and hepatitis positive patients
Where it's running
-
CHU Amiens
Amiens, France Recruiting
Study contacts
- Study coordinator: Romuald Mentaverri, Pr
- Email: romuald.mentaverri@u-picardie.fr
- Phone: 03 22 887104
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.