Using gel sheets to treat burn scars
Official title: Randomized, Controlled, Within-patient Study to Evaluate the Efficacy of a Nonsilicone Gel Sheet for the Treatment of Hypertrophic Scar in Adult Burn Survivors
Run by Centre hospitalier de l'Université de Montréal (CHUM) · NCT05429411 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing whether a special gel sheet can help prevent and improve scars from deep burns in people who have experienced these injuries.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 16 Years to 100 Years |
| Sex | All |
| Enrollment | 36 (estimated) |
| Sponsor | Centre hospitalier de l'Université de Montréal (CHUM) Academic / other |
| Locations | 1 site (Montréal) |
| Trial ID | NCT05429411 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 16 and older who have been admitted for thermal burn treatment and exhibit clinical signs of hypertrophic scars.
✕Probably not a fit
Patients with mature scars, keloid scars, or those with specific dermatological conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of a non-silicone gel sheet in preventing and treating hypertrophic scars resulting from deep dermal burn injuries. Participants will wear the gel sheets for increasing durations, starting from 4 hours and gradually progressing to over 21 hours daily. The study employs a randomized, controlled, within-patient design, comparing the treatment site with a patient-matched control site to ensure accurate assessment of outcomes. The use of validated electronic measurement tools aims to provide objective data on scar improvement.
Why it matters
Potential benefit: If successful, this treatment could significantly improve the management of hypertrophic scars, enhancing patient quality of life.
How similar studies have gone: Previous studies on gel sheets for scar treatment have shown mixed results, indicating a need for more rigorous evaluation like this one.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Females and males, of any race * 16 years or older who were admitted to the Montreal Burn Centre for the treatment of a thermal burn injury * Scar sites that show clinical evidence of HSc (\>2.034 mm thick as measured by high frequency ultrasound and hyperaemic - defined as Mexameter erythema index \>300) * Understand French or English * Signed the informed patient consent form. Exclusion Criteria: * Suspected or known allergy to ultrasound gel * Formed keloid scars * Scar site that are mature (defined as Mexameter erythema index \<300 and \<2.034 mm thick) * Diagnosed with a psychiatric illness that will impair the subjects ability to participate in the study or provide informed consent * Mechanism of injury is an electrical, chemical, or cold injury * Dermatological condition such as psoriasis, eczema, etc., in the region of the evaluation site, which in the investigator's opinion, may interfere with the study results.
Where it's running
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Villa Medica Rehabilitation Hospital
Montréal, Canada Recruiting
Study contacts
- Study coordinator: Bernadette Nedelec
- Email: bernadette.nedelec@mcgill.ca
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Using laser therapy to improve burn scars
This study is testing if a special laser treatment can help improve the appearance and feel of burn scars that are 6 to 12 months old.
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Using pulsed dye laser therapy to improve burn scars
This study is testing whether pulsed dye laser therapy can improve the appearance and feel of burn scars in people with recent burn injuries.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.