Using FAPI PET-CT to diagnose endometriosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the feasibility of FAPI PET-CT imaging for diagnosing endometriosis in patients scheduled for surgery. Participants will receive a single injection of FAPI and undergo multiple imaging sessions to assess the presence of endometriotic lesions. The results from the imaging will be compared with surgical findings and pathology to determine accuracy. The study aims to provide a non-invasive method for better pre-operative planning and lesion mapping.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female participants aged 18-45 years
* Clinical suspicion of endometriosis based on symptoms
* Scheduled for diagnostic/therapeutic laparoscopic surgery
* Ability to understand and provide written informed consent
* Completed and signed Radiation Exposure Documentation Form

Exclusion Criteria:

* Pregnant women or women who are breastfeeding
* History of pelvic radiation therapy
* Known active malignancy
* Exposure to ionizing radiation for medical purposes within 12 months prior to enrollment

Where it's running

• Ziv Medical Center
  Safed, Israel Recruiting

Study contacts

• Study coordinator: Israel Sandler, MD
• Email: israels@ziv.gov.il
• Phone: +972-527-362280

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Comparing different techniques to treat endometriosis

  This study is testing different methods to treat endometriosis, like laser and heat techniques, to see which one works best for relieving pain in women who are already having surgery for the condition.

  Recruiting TriHealth Inc. · Cincinnati, Ohio · NCT06414083

• Postoperative Pain Trajectories After Endometriosis Surgery

  This study tests how pain changes after endometriosis surgery and whether perioperative pain testing can predict who will have ongoing pain.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07882498

• Imaging endometriosis with a special PET tracer in adult women

  This study tests whether a PET/CT scan using [18F]AlF-FAPI-74 can help detect endometriosis lesions in women who are planning laparoscopy.

  Recruiting Universitaire Ziekenhuizen KU Leuven · Leuven · NCT07876648

• Fiber supplement for digestive symptoms in endometriosis

  A fiber-based supplement is being tested to see if it is safe and helps with gut and vaginal microbiomes and digestive symptoms in women with endometriosis.

  Recruiting LOAM Science · San Francisco, California · NCT07875062

• Stellate ganglion block and dexmedetomidine for better sleep after gynecologic laparoscopy

  The study tests whether giving a preoperative stellate ganglion block plus intraoperative dexmedetomidine improves sleep after laparoscopic gynecologic surgery in women.

  Recruiting The Second People's Hospital of Huai'an · Huai'an, Jiangsu · NCT07860203

• Atypical Endometriosis: Histology, Immunophenotype and Molecular Features

  Researchers will look at how endometriotic tissue that looks atypical under the microscope relates to clinical features and ultrasound findings to better separate benign from potentially atypical lesions.

  Recruiting Casa di Cura Dott. Pederzoli · Peschiera del Garda, Verona · NCT07816133

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.