Understanding the Aorta's Function and Structure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the heterogeneity and regional differences in the aorta's physicomechanical properties, which are crucial for effective blood flow distribution. It will collect clinical data from both healthy volunteers and patients suffering from aortic stenosis and aortic aneurysms to better understand how these variations affect hemodynamics and contribute to conditions like large artery stiffness. The study focuses on the relationship between the aorta's structure and its function, particularly in relation to organ health. By systematically gathering this data, the research seeks to fill gaps in knowledge regarding aortic disease.

Why it matters

Who can join: the full rules

1. apparently healthy volunteers

   Inclusion Criteria:

   • Healthy volunteers

   Exclusion Criteria:
   * \< 18 years
   * Active Medication
   * Cardiovascular Disease
   * MRI not possible
2. Patients with Aortic Stenosis

   Inclusion Criteria:

   • Patients suffering from 3rd drgree Aortic Stenosis

   Exclusion Criteria:
   * \< 18 years
   * MRI not possible
3. Patients with Aortic Aneurysms

Inclusion Criteria:

• Patients suffering from Aortic Aneurysms

Exclusion Criteria:

* \< 18 years
* MRI not possible

Where it's running

• Christine Quast
  Düsseldorf, Germany Recruiting

Study contacts

• Principal investigator: Christine Quast, MD — Division of Cardiology, Pulmonary Disease and Vascular Medicine
• Study coordinator: Christine Quast, MD
• Email: Christine.Quast@med.uni-duesseldorf.de
• Phone: +492118118800

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.