Systematic 14-day ambulatory heart monitoring after TAVI
Official title: Systematic Ambulatory ECG Monitoring Following TAVI: A Prospective Randomized Trial.
Run by Institut universitaire de cardiologie et de pneumologie de Québec, University Laval · NCT07739316 · Data updated 2026-11-12
After TAVI, patients with certain heart conduction abnormalities will try 14 days of wearable ECG monitoring to see if it lowers the chances of sudden death, symptomatic heart rhythm problems, or stroke within a year compared to standard follow-up.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 754 (estimated) |
| Sponsor | Institut universitaire de cardiologie et de pneumologie de Québec, University Laval Academic / other |
| Locations | 1 site (Québec, Quebec) |
| Status | Recruiting |
| Started | October 23, 2026 |
| Main results expected | December 2028 |
| Study ends | December 2028 |
| Registry record updated | November 4, 2026 |
| Trial ID | NCT07739316 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults who had a successful TAVI, were discharged within 72 hours, and have at least one ECG abnormality at discharge (QRS ≥120 ms or PR ≥200 ms) and no pacemaker.
✕Probably not a fit
Patients without post-discharge conduction abnormalities or those with a pacemaker may derive little to no additional benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This multicenter, randomized trial tests whether 14 days of ambulatory ECG monitoring after hospital discharge improves outcomes versus standard post-discharge care in adults who had successful TAVI and have conduction abnormalities. Participants are randomized soon after discharge and all receive routine follow-up at 30 days and 1 year. The study focuses on detecting clinically significant arrhythmias early, with the aim of reducing death, arrhythmic events, and stroke by enabling timely interventions. The trial builds on the idea that continuous rhythm surveillance after early discharge may reveal problems that would otherwise be missed. Enrollment targets adults with specific ECG abnormalities and without prior pacemaker implantation.
Why it matters
Potential benefit: If successful, patients could have earlier detection and treatment of dangerous heart rhythms, potentially reducing serious events after TAVI.
How similar studies have gone: Prior observational work suggests ambulatory monitoring can detect significant arrhythmias after TAVI, but randomized evidence is limited and this study extends that to a controlled setting.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age \>18 years * Successful TAVI procedure. * Hospitalization discharge ≤72 hrs following the TAVI procedure. * Presence of at least 1 ECG abnormality at hospital discharge (QRS ≥120 ms OR PR ≥200 ms) Exclusion Criteria: * Pacemaker implantation (pre- TAVI or during hospitalization after the procedure). * TAVI valve-in-valve procedure * Any complication or logistic reason precluding hospital discharge ≤72 hrs following the TAVI procedure. * Impossibility to obtain signed informed consent.
Where it's running
-
Institut universitaire de cardiologie et de pneumologie de Québec - UL
Québec, Quebec, Canada Recruiting
Study contacts
- Principal investigator: Josep Rodes-Cabau, MSc — Fondation IUCPQ
- Study coordinator: Josep Rodes-Cabau, MD, PhD
- Email: josep.rodes-cabau@criucpq.ulaval.ca
- Phone: 14186568711
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.