Understanding parental decisions in pediatric cancer clinical trials

U-DECIDE: The Decision To Enroll In Therapeutic Clinical Trials In A Pediatric Cancer Clinical Network

Observational St. Jude Children's Research Hospital · NCT05454618

This study looks at what factors influence parents' choices about enrolling their child in cancer clinical trials to better understand their decisions.

Quick facts

Study typeObservational
Enrollment400 (estimated)
SexAll
SponsorSt. Jude Children's Research Hospital Academic / other
Locations1 site (Memphis, Tennessee)
Trial IDNCT05454618 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore the factors influencing parents' decisions regarding their child's participation in therapeutic clinical trials within a pediatric cancer network. It will collect sociodemographic data and assess social determinants of health through surveys administered to parents or legal guardians of newly diagnosed pediatric oncology patients. The study will also investigate the associations between these factors and parents' attitudes towards clinical trial enrollment, utilizing both quantitative and qualitative methods for a comprehensive analysis.

Who should consider this trial

Good fit: Ideal candidates for this study are English or Spanish speaking parents or legal guardians of children aged 0-18 with newly diagnosed cancer.

Not a fit: Parents of children with relapsed or recurrent cancer or benign neoplasms may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of barriers to clinical trial enrollment, leading to improved strategies for increasing participation in pediatric cancer research.

How similar studies have performed: While studies have explored parental attitudes towards clinical trials, this specific focus on sociodemographic factors and decision-making in a pediatric oncology context is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All English or Spanish speaking parents/LARs of patients 0-18 years of age with newly diagnosed cancer in the Affiliate network.

Exclusion Criteria:

* Parents of children with relapsed or recurrent disease, or those with benign neoplasms.

Where this trial is running

Memphis, Tennessee

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Knowledge, Attitudes, PracticeParentPediatric Oncology PatientsCaregiversBarriers to Enrollment on a Therapeutic TrialParent Navigator ProgramAffiliate NetworkDecision Making
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.