Understanding factors that help cancer patients quit smoking after treatment

A Prospective Study on the Factors Sustaining Tobacco Abstinence in Patients Treated With Radio-chemotherapy or Radiotherapy Alone for Head and Neck or Lung Cancer

Centre Oscar Lambret · NCT06910566

This study is trying to find out what helps cancer patients who have had treatment for head and neck or lung cancer to quit smoking and stay smoke-free for at least six months.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexAll
SponsorCentre Oscar Lambret (other)
Locations1 site (Lille)
Trial IDNCT06910566 on ClinicalTrials.gov

What this trial studies

The TABAC STOP ORL POUMON study evaluates the factors influencing long-term smoking cessation in patients with head and neck or lung cancer undergoing radiotherapy or chemoradiotherapy. This single-center observational study follows patients at 1, 6, and 12 months post-treatment, assessing their smoking status and various factors related to nicotine dependence. The primary goal is to determine the proportion of patients who remain smoke-free at 6 months, while secondary objectives explore reasons for relapse and changes in dependence levels. A total of 100 patients will be enrolled to ensure robust statistical analysis.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 and older diagnosed with head and neck or lung cancer who are current or former smokers undergoing curative treatment.

Not a fit: Patients receiving palliative treatment or those under guardianship may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into effective strategies for smoking cessation among cancer patients, potentially improving their overall health outcomes.

How similar studies have performed: Other studies have shown success in understanding smoking cessation in cancer patients, making this approach both relevant and potentially impactful.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria :

* Patient aged 18 years or older
* Diagnosed with head and neck cancer or lung cancer
* Undergoing curative treatment with chemoradiotherapy, radiotherapy alone, or stereotactic radiotherapy
* Current or former smoker
* Patient covered by a social security scheme
* Patient informed and having given consent for data collection

Patients with human papillomavirus (HPV) may also be included

Exclusion Criteria :

* Patient receiving palliative treatment
* Patient under guardianship or curatorship

Study Exit Criteria :

- Protocol-defined exit : After the 12-month consultation

Early exit :

* Withdrawal of consent for data collection
* Death of the patient

Where this trial is running

Lille

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Smoking Cessation, Nicotine Addiction, Nicotine Dependence, Smoking, Head and Neck Neoplasms, Tobacco abstinence, Head and neck cancer, Smoking cessation

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.