Ultrasound-Guided Rectus Sheath Block vs Local Infiltration for Pain After Laparoscopic Gallbladder Removal
Official title: Comparison of the Analgesic Effects of Local Anesthetic Infiltration and Ultrasound-Guided Rectus Sheath Block in Laparoscopic Cholecystectomy Operations: A Prospective Randomized Controlled Study
Run by Sisli Hamidiye Etfal Training and Research Hospital · NCT07582029 · Data updated 2026-11-12
This trial tests whether a rectus sheath block or direct local anesthetic infiltration provides better pain control after laparoscopic cholecystectomy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Sisli Hamidiye Etfal Training and Research Hospital Academic / other |
| Locations | 1 site (Istanbul) |
| Status | Recruiting |
| Started | May 12, 2026 |
| Main results expected | November 12, 2026 |
| Study ends | December 12, 2026 |
| Registry record updated | October 16, 2026 |
| Trial ID | NCT07582029 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18–65 with ASA I–II status undergoing elective laparoscopic cholecystectomy who have no contraindications to regional anesthesia.
✕Probably not a fit
Patients with higher surgical risk (ASA III-IV), infection at the block site, coagulopathy, or allergies to study medications may not benefit and are excluded.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective randomized study compares two regional anesthesia techniques, rectus sheath block and local anesthetic infiltration, used during laparoscopic cholecystectomy to manage postoperative pain. It examines effects on pain scores, opioid use, and analgesia-related side effects. Participants are adults aged 18–65 with ASA I–II status undergoing the procedure. The trial aims to determine which technique offers superior analgesia with fewer opioid requirements and adverse effects. Conducted at Sisli Hamidiye Etfal Training and Research Hospital in Istanbul, the study adheres to standard postoperative pain management practices while isolating the analgesic technique as the variable of interest.
Why it matters
Potential benefit: If successful, patients may experience better pain relief with less opioid use after laparoscopic gallbladder removal.
How similar studies have gone: Previous studies support regional anesthesia techniques for postoperative pain, but direct head-to-head comparisons of rectus sheath block versus local infiltration in this setting are limited, making this trial relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ASA (American Society of Anesthesiologists) class I-II patients * Patients aged between 18 and 65 years * Patients undergoing laparoscopic cholecystectomy surgery Exclusion Criteria: * ASA class III-IV patients * Patients undergoing emergency surgery * Relatives of patients who do not provide consent * Presence of chronic pain * Chronic opioid use * Presence of local anesthetic allergy * Ibuprofen allergy * Paracetamol allergy * Presence of infection at the block site * Coagulopathy * Increased intracranial pressure * Pre-existing neurological deficit * Severe organ failure * Mental retardation * Anatomical deformity
Where it's running
-
Sisli Hamidiye Etfal Training Hospital
Istanbul, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Leyla Kilinc — şişli etfal eğitim araştırma hastanesi
- Study coordinator: Leyla Kilinc
- Email: leylaturkoglu@hotmail.com
- Phone: +90 532 417 02 44
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.