True Muscle Transplantation vs Augmented Semi Hang-Back Recession for Large Angle Exotropia
Official title: True Muscle Transplantation Surgery Versus Augmented Semi Hang Back Recession in Large Angle Exotropia: Evaluation of Efficacy and Lateral Gaze Incomitance
Run by Minia University · NCT07784842 · Data updated 2026-11-12
A randomized trial tests whether true muscle transplantation works better than augmented semi hang-back recession for correcting large-angle exotropia in adults.
Quick facts
| Study type | Interventional |
|---|---|
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Minia University Academic / other |
| Locations | 1 site (Minya, Minya Governorate) |
| Status | Recruiting |
| Started | March 1, 2026 |
| Main results expected | October 2026 |
| Study ends | January 2027 |
| Registry record updated | August 25, 2026 |
| Trial ID | NCT07784842 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults with exotropia greater than 50 prism diopters who have not had previous squint surgery.
✕Probably not a fit
Patients with extensive ocular surface disease or those unable to undergo general anesthesia may not benefit from these approaches.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized, interventional trial compares two surgical approaches for large-angle exotropia. Forty participants with exotropia greater than 50 prism diopters and no prior squint surgery will be assigned to either true muscle transplantation or augmented semi hang-back recession. Participants will be followed for six months to measure eye alignment and overall surgical success. The study is conducted at Minya University Hospital under the leadership of Hassnaa Mohamed Abdelhameed Ahmed.
Why it matters
Potential benefit: If successful, the preferred procedure could improve eye alignment and quality of life for people with large-angle exotropia.
How similar studies have gone: Prior research in strabismus has explored similar surgical strategies, but this direct head-to-head comparison is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients with large angle exotropia more than 50 prism diopters. 2. No previous squint surgery. Exclusion Criteria: 1. Patients with severe ocular surface diseases as ocular cicatricial pemphigoid and severe dry eye. 2. Severe systemic illness that prevents general anesthesia
Where it's running
-
Minya University Hospital - Ophthalmology Department
Minya, Minya Governorate, Egypt Recruiting
Study contacts
- Study coordinator: Hassnaa Mohamed Abdelhameed, Assistant lecturer
- Email: hasnaa.abdelhamid@mu.edu.eg
- Phone: +201158861290
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.