Predictors of In-Hospital Death in Severe Abdominal Injury

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this prospective observational study, researchers will enroll consecutive patients aged 16 and older with severe abdominal injuries admitted to a tertiary trauma center over 12 months. The project aims to examine early physiologic and biochemical markers and existing risk scores to understand how well they predict mortality in a high-volume, resource-constrained setting. The study plans to recruit about 430 evaluable patients and will use routine trauma care data to develop or validate a prediction model for in-hospital mortality. Inclusion requires severe abdominal injury, presentation within 24 hours, and informed (or deferred) consent; key exclusions include death on arrival and isolated minor injuries. Lead sponsorship is from Minia University, with the study conducted at Minia University Hospitals Trauma Unit.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 16 years or older.
* Abdominal trauma, blunt or penetrating, meeting at least one criterion for severity: Abbreviated Injury Scale (AIS) for the abdominal region of 3 or more; and/or an abdominal injury requiring emergency laparotomy, laparoscopy or angioembolisation; and/or admission to the intensive care unit for management of an abdominal injury.
* Presentation within 24 hours of injury.
* Informed consent provided by the patient or, for incapacitated patients, by a legal representative, with deferred consent procedures as specified in the protocol.

Exclusion Criteria:

* Death on arrival, or within the first 15 minutes of admission before meaningful resuscitation or data capture.
* Isolated minor abdominal injury not meeting the severity definition (AIS-abdomen below 3 and not requiring operative or radiological intervention or critical-care admission).
* Transfer out of the centre before the primary outcome can be ascertained.
* Known pregnancy (managed on a separate obstetric-trauma pathway).
* Declined consent.

Where it's running

• Minia University Hospitals /Trauma unit- Department of Surgery, Faculty of Medicine, Minia University
  Minya, Minya Governorate, Egypt Recruiting

Study contacts

• Principal investigator: Saleh K Saleh, MD — Minia University
• Study coordinator: Saleh K Saleh, MD
• Email: salehkhairy@mu.edu.eg
• Phone: 01201765401

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.