Transversalis fascia plane block vs low-dose intrathecal morphine for open inguinal hernia repair

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults undergoing elective unilateral open inguinal hernia repair under spinal anesthesia are randomized to receive either a transversalis fascia plane block with local anesthetic or low-dose intrathecal morphine, alongside the same spinal anesthesia and multimodal postoperative analgesia. The study assesses pain scores, analgesic use, opioid-related adverse effects, and recovery within the first 24 hours after surgery, with exploratory follow-up for chronic pain if data allow. It is assessor-blinded and compares a regional block approach to intrathecal opioid in a controlled setting. The intervention group receives a unilateral TFP block before surgery; the control group receives intrathecal morphine with no block. All participants are adults aged 18–80 with ASA I–III planned for spinal anesthesia. Safety outcomes and tolerability are also recorded.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients aged 18-80 years
* Patients scheduled for elective unilateral open inguinal hernia repair
* ASA physical status I-III
* Patients planned to undergo spinal anesthesia
* Patients able to understand and report postoperative pain scores
* Patients who provide written informed consent

Exclusion Criteria:

* Refusal to participate
* Bilateral inguinal hernia repair
* Recurrent inguinal hernia repair
* Emergency, incarcerated, or strangulated hernia
* Need for general anesthesia
* Contraindication to spinal anesthesia
* Coagulopathy or anticoagulant use contraindicating neuraxial or peripheral block
* Infection at the injection site
* Known allergy to local anesthetics, morphine, or study medications
* Chronic opioid use
* Preoperative chronic groin pain or neuropathic pain history
* Severe hepatic or renal failure
* Neurological or psychiatric condition preventing communication or pain assessment
* Expected inability to complete postoperative follow-up

Where it's running

• Hitit university
  Çorum, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Sibel Onen Ozdemir, MD
• Email: sibelonen89@gmail.com
• Phone: +905442892194

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• PECS II vs SPSIP nerve blocks for pain after mastectomy

  This study tests whether two ultrasound-guided nerve blocks (PECS II and SPSIP) differ in how much opioid patients need after mastectomy.

  Recruiting Bursa City Hospital · Nilufer, Bursa · NCT07929090

• Palatal Shield Technique to Reduce Pain and Improve Healing After Free Gingival Graft

  This randomized trial tests whether a collagen sponge with a protective palatal shield made of flowable resin helps reduce pain and improve healing after free gingival graft harvest.

  Recruiting Cairo University · Cairo, Cairo Governorate · NCT07926516

• Perfusion Index to Measure Postoperative Pain in Kids After Adenotonsillectomy

  This study tests whether the perfusion index can reliably reflect pain levels in children aged 1–12 after adenotonsillectomy, comparing standard care with an added glossopharyngeal nerve block.

  Recruiting Istanbul University · Istanbul, Istanbul · NCT07915804

• Anterior Knee Nerves Block vs Femoral Nerve Block for Knee Arthroscopy

  This trial tests whether an anterior nerves of the knee (ANK) block provides similar pain relief to a femoral nerve block after knee arthroscopy in adults, aiming to reduce quadriceps weakness.

  Recruiting Van Training and Research Hospital · Van · NCT07910500

• Natural Biopolymer-Based Irrigant for Root Canal Cleaning

  This trial tests a chitosan nanoparticle irrigant to improve cleaning and disinfection in single-rooted teeth with asymptomatic pulp necrosis undergoing endodontic treatment.

  Recruiting Minia University · Minya · NCT07901127

• Postoperative Pain Trajectories After Endometriosis Surgery

  This study tests how pain changes after endometriosis surgery and whether perioperative pain testing can predict who will have ongoing pain.

  Recruiting Centre Hospitalier Universitaire, Amiens · Amiens · NCT07882498

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.