Tracking sensory changes after a stroke to improve walking and balance
Tracking the Development and Influence of Post-Stroke Sensory Reweighting on Walking and Balance Outcomes
This study is trying to see how changes in feeling and movement after a stroke affect walking and balance in stroke survivors to help improve their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 45 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Cincinnati Academic / other |
| Locations | 1 site (Cincinnati, Ohio) |
| Trial ID | NCT06727097 on ClinicalTrials.gov |
What this trial studies
This observational study aims to longitudinally assess post-stroke sensory reweighting and its neuroanatomical correlates to understand their impact on walking and balance outcomes. It focuses on stroke survivors who experience significant walking impairments and balance issues due to diminished sensorimotor integration. By utilizing advanced techniques such as posturography, walking speed assessments, and MRI, the study seeks to identify reliable physiological markers that can inform targeted rehabilitation strategies. The goal is to enhance recovery in the critical early stages following an ischemic stroke.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have experienced their first ischemic stroke and are able to provide consent.
Not a fit: Patients with pre-existing conditions that significantly affect mobility or those with severe stroke-related disabilities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved rehabilitation strategies that enhance walking and balance in stroke survivors, reducing the risk of falls and associated complications.
How similar studies have performed: While this approach is innovative, similar studies have shown promise in understanding the relationship between neuroanatomical changes and rehabilitation outcomes in stroke patients.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. First ever clinical stroke 2. Stroke due to ischemia 3. Age 18 years or older 4. Ability to consent by patient (not surrogate), any time prior to acute hospital discharge Exclusion Criteria: 1. Pre-stroke dependence (modified Rankin Scale score of 3 or more) 2. Isolated brainstem or cerebellar stroke 3. Bilateral acute strokes 4. Co-enrollment in a trial of an intervention through six-month follow-up 5. Inability to maintain follow-up with study procedures through six-month follow-up 6. Contraindication to non-contrast MRI 7. Low likelihood of survival beyond the acute hospitalization, such as malignant cerebral edema 8. Pre-existing co-morbid conditions that significantly affects vision, somatosensory function, vestibular system, orthostasis, coordination or mobility 9. Post stroke mRS\>4 or discharge to hospice
Where this trial is running
Cincinnati, Ohio
- University of Cincinnati College of Medicine — Cincinnati, Ohio, United States (Recruiting)
Study contacts
- Principal investigator: Oluwole Awosika, MD, MSCR — University of
- Study coordinator: oluwole Awosika, MD, MSCR
- Email: awosikoe@ucmail.uc.edu
- Phone: +1 513 558 2919
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.