Tracking sensory changes after a stroke to improve walking and balance
Official title: Tracking the Development and Influence of Post-Stroke Sensory Reweighting on Walking and Balance Outcomes
Run by University of Cincinnati · NCT06727097 · Data updated 2026-11-12
This study is trying to see how changes in feeling and movement after a stroke affect walking and balance in stroke survivors to help improve their recovery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 45 (estimated) |
| Sponsor | University of Cincinnati Academic / other |
| Locations | 1 site (Cincinnati, Ohio) |
| Status | Recruiting |
| Started | November 1, 2024 |
| Main results expected | July 31, 2027 |
| Study ends | August 30, 2027 |
| Registry record updated | September 2, 2026 |
| Trial ID | NCT06727097 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults aged 18 and older who have experienced their first ischemic stroke and are able to provide consent.
✕Probably not a fit
Patients with pre-existing conditions that significantly affect mobility or those with severe stroke-related disabilities may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to longitudinally assess post-stroke sensory reweighting and its neuroanatomical correlates to understand their impact on walking and balance outcomes. It focuses on stroke survivors who experience significant walking impairments and balance issues due to diminished sensorimotor integration. By utilizing advanced techniques such as posturography, walking speed assessments, and MRI, the study seeks to identify reliable physiological markers that can inform targeted rehabilitation strategies. The goal is to enhance recovery in the critical early stages following an ischemic stroke.
Why it matters
Potential benefit: If successful, this study could lead to improved rehabilitation strategies that enhance walking and balance in stroke survivors, reducing the risk of falls and associated complications.
How similar studies have gone: While this approach is innovative, similar studies have shown promise in understanding the relationship between neuroanatomical changes and rehabilitation outcomes in stroke patients.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. First ever clinical stroke 2. Stroke due to ischemia 3. Age 18 years or older 4. Ability to consent by patient (not surrogate), any time prior to acute hospital discharge Exclusion Criteria: 1. Pre-stroke dependence (modified Rankin Scale score of 3 or more) 2. Isolated brainstem or cerebellar stroke 3. Bilateral acute strokes 4. Co-enrollment in a trial of an intervention through six-month follow-up 5. Inability to maintain follow-up with study procedures through six-month follow-up 6. Contraindication to non-contrast MRI 7. Low likelihood of survival beyond the acute hospitalization, such as malignant cerebral edema 8. Pre-existing co-morbid conditions that significantly affects vision, somatosensory function, vestibular system, orthostasis, coordination or mobility 9. Post stroke mRS\>4 or discharge to hospice
Where it's running
-
University of Cincinnati College of Medicine
Cincinnati, Ohio, United States Recruiting
Study contacts
- Principal investigator: Oluwole Awosika, MD, MSCR — University of
- Study coordinator: oluwole Awosika, MD, MSCR
- Email: awosikoe@ucmail.uc.edu
- Phone: +1 513 558 2919
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
AI-based tools to help diagnose, treat and predict stroke outcomes across multiple hospitals
This study tests AI-powered tools on real-world stroke patients to see if they can improve pre-hospital triage, diagnosis, and outcome prediction while data stay securely within each hospital.
-
Remote ischemic conditioning for post-stroke insomnia
A 136-person, randomized study will test whether a non-invasive arm-cuff procedure done twice daily for 90 days can improve sleep after a first ischemic stroke in adults 18–80.
-
Ear-based nerve stimulation to help sleep after a stroke
A device that delivers vagal nerve stimulation through the ear is tested to see if it helps stroke patients in rehab sleep better.
-
Theta Burst Stimulation to Help Stroke Recovery (Upper and Lower Limbs)
This trial tests whether applying theta burst stimulation to the motor cortex, in combination with standard rehabilitation, helps people over 45 who recently had a first ischemic stroke recover arm and leg movement.
-
Preventing another ischemic stroke with a smart bracelet and app
This study tests whether a digital prevention program using a wearable and a mobile app can help people who recently had an ischemic stroke reduce the chance of another stroke and improve risk-factor control.
-
Photon-counting CT to check intracranial stents
This study tests whether ultra-high-resolution photon-counting CT can reliably visualize intracranial stents and detect in-stent restenosis during follow-up of patients with prior stents.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.