A novel multi angular isometric lumbar exercise for chronic low back pain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial compares Multi Angular Isometric Lumbar Exercise (MAILE) to traditional lumbar stabilization and core stability programs for nonspecific chronic low back pain. Participants ages 18–60 with chronic low back pain lasting more than 3 months will be stratified and randomized, with single-blind assessment and a sealed envelope allocation to reduce bias. The study focuses on pain intensity, functional disability, functional stability of the lumbo-pelvic-hip complex, and muscle strength, to determine if MAILE provides superior or more cost-efficient benefits. The protocol is grounded in a motor control and stability impairment model and emphasizes neuromuscular coordination and load management. A power calculation targets 80% power to detect a meaningful effect size, with an estimated sample size near 98 after accounting for dropouts.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Participants eligible for this study must meet the following criteria:

Age between 18-60 years Diagnosed with Nonspecific Chronic Low Back Pain (NCLBP) by an orthopedic doctor, general physician, neurologist, or primary healthcare doctor Low back pain lasting for more than 3 months (pain between T12 and the gluteal fold) Must have had more pain-free days than painful days during the past year Pain located mainly in the lower lumbar region (L4/L5 and/or L5/S1) Presence of positive prone instability test Presence of aberrant movement during motion testing Straight Leg Raise \> 91° BMI between 20-30

Presence of one or more of the following:

Pain worsens with sustained end-range movements or positions Lumbar hypermobility on segmental motion assessment Mobility deficits of the thorax and lumbopelvic/hip regions Reduced trunk or pelvic muscle strength and endurance Movement coordination impairments during work, recreational, or daily functional activities

Patients must also:

Be willing and able to safely participate in an exercise program Have no cognitive impairment limiting participation

Exclusion Criteria:

Participants will be excluded if they have any of the following:

Radiculopathy (confirmed through clinical and neurological assessment) Cauda equina symptoms (e.g., bowel/bladder dysfunction, perianal numbness) Spinal deformities (fracture, infection, tumor) Severe osteoporosis History of lumbar spine surgery Pregnancy Psychiatric illness or cognitive impairment (e.g., dementia) Substance abuse

Use of medications:

Current anticoagulants or corticosteroids Long-term steroid use (≥7.5 mg for \>6 months) Recent or significant trauma Pain or neurological symptoms during positioning or lever application (unsafe for intervention) Cardiac conditions Cancer

Other significant medical conditions, including:

Rheumatologic disorders Spinal infections Prior back surgery

Where it's running

• Outpatient Physiotherapy HMGH, Hamad Medical Corporation
  Doha, Qatar Recruiting

Study contacts

• Principal investigator: Yadulla Syed, MPT Ortho — Hamad Medical Corporation
• Study coordinator: Yadulla Syed, MPT
• Email: Ysayed@hamad.qa
• Phone: +97455503640

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.