Three body positions to reduce hypoxemia after painless GI endoscopy
Official title: Effects of Lateral Decubitus Head-up Position, Supine Head-up Position, and Standard Lateral Decubitus Position on Hypoxemia During Recovery in Patients Undergoing Painless Gastroscopy and Colonoscopy: A Multicenter, Three-arm Randomized Controlled Trial
Run by General Hospital of Ningxia Medical University · NCT07587970 · Data updated 2026-11-12
This trial tests whether three different patient positions during recovery after painless gastroscopy and colonoscopy can lower the chance of low oxygen levels in adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1617 (estimated) |
| Sponsor | General Hospital of Ningxia Medical University Academic / other |
| Locations | 1 site (Yinchuan, Ningxia) |
| Status | Recruiting |
| Started | May 8, 2026 |
| Main results expected | December 31, 2026 |
| Study ends | January 31, 2027 |
| Registry record updated | June 17, 2026 |
| Trial ID | NCT07587970 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) scheduled for painless esophagogastroduodenoscopy and/or colonoscopy, with ASA I–III, and capable of consent, including those with common comorbidities.
✕Probably not a fit
Patients with severe cardiovascular/cerebrovascular disease or other exclusion criteria may not experience benefit from repositioning.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This multicenter trial randomizes adults undergoing painless esophagogastroduodenoscopy and/or colonoscopy to one of three recovery positions: lateral decubitus with head elevation, supine with head elevation, or standard lateral decubitus. The goal is to see which position most effectively reduces postoperative hypoxemia while being simple and non-invasive. The study uses standard anesthesia and monitors respiratory status to compare incidence of hypoxemia across groups. By broadening eligibility to include common comorbidities, the trial aims to reflect routine practice and inform non-pharmacologic management of respiratory function after these procedures.
Why it matters
Potential benefit: If successful, adopting the best recovery position could reduce hypoxemia and improve safety and recovery time after painless GI procedures.
How similar studies have gone: Other perioperative positioning studies have shown position-related changes in respiratory parameters, but this trial specifically targets recovery hypoxemia after painless GI procedures.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age ≥ 18 years. 2. Both sexes. 3. American Society of Anesthesiologists (ASA) physical status classification I-III. 4. Scheduled for combined painless esophagogastroduodenoscopy/colonoscopy or either of the two procedures. 5. Ability to understand the study protocol and provide written informed consent. 6. A broad set of inclusion criteria was adopted to enroll a patient population that better reflects routine clinical practice. The study aimed to enhance the generalizability of the findings by including patients with various comorbidities, such as preprocedural hypoxemia (room-air SpO₂ ≤ 90%), history of pulmonary surgery, obstructive sleep apnea (OSA), and other pulmonary conditions (including asthma, COPD, chronic bronchitis, emphysema, and pulmonary bullae). Exclusion Criteria: 1. Severe cardiovascular or cerebrovascular diseases. 2. Pregnant patients. 3. History of hypersensitivity to ciprofol. Withdrawal Criteria: 1. Endotracheal intubation required during the procedure. 2. Voluntary withdrawal requested by the patient or their legal representative.
Where it's running
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General hospital of Ningxia medical university, Yinchuan, Ningxia
Yinchuan, Ningxia, China Recruiting
Study contacts
- Study coordinator: xiaoyong wei, Master's degree
- Email: weixy9912@126.com
- Phone: 86-951-674-3252
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.