Side-lying versus back-lying position to reduce low oxygen after painless gastroscopy or colonoscopy
Official title: Effect of Lateral Versus Supine Positions on Postoperative Hypoxemia in Patients Undergoing Painless Gastroscopy and Colonoscopy: A Prospective Randomized Controlled Study
Run by General Hospital of Ningxia Medical University · NCT07545642 · Data updated 2026-11-12
This test sees if lying on your side instead of on your back during recovery after a painless gastroscopy or colonoscopy cuts the chance of low oxygen levels in adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 960 (estimated) |
| Sponsor | General Hospital of Ningxia Medical University Academic / other |
| Locations | 1 site (Yinchuan, Ningxia) |
| Status | Recruiting |
| Started | April 22, 2026 |
| Main results expected | June 18, 2026 |
| Study ends | July 30, 2026 |
| Registry record updated | June 24, 2026 |
| Trial ID | NCT07545642 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18 years) scheduled for painless gastroscopy and/or colonoscopy under sedation, classified ASA I–III and able to give informed consent, including those with common pulmonary conditions, are eligible.
✕Probably not a fit
Patients with severe cardiovascular or cerebrovascular disease, pregnant patients, those with hypersensitivity to ciprofol, or those who require endotracheal intubation during the procedure are unlikely to benefit from this positioning intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study assigns adults having painless esophagogastroduodenoscopy and/or colonoscopy to recover either in the lateral (side-lying) or supine (back-lying) position and monitors oxygen saturation in the post-procedure period. The trial uses prospective real-world data and includes a broad patient mix (ASA I–III) to reflect routine clinical practice, including patients with common pulmonary comorbidities. The primary focus is the incidence of postprocedural hypoxemia during recovery, with comparisons between the two position groups. The intervention is non-invasive, simple to implement, and intended as a low-cost optimization for standard recovery care.
Why it matters
Potential benefit: If successful, this could provide a simple, non-invasive, low-cost way to lower the risk of low oxygen episodes after sedated GI endoscopy.
How similar studies have gone: Emerging evidence during sedation suggests lateral positioning reduces intra-procedural hypoxemia, but high-quality data specifically focused on the recovery phase are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age ≥ 18 years. 2. Both sexes. 3. American Society of Anesthesiologists (ASA) physical status classification I-III. 4. Scheduled for combined painless esophagogastroduodenoscopy/colonoscopy or either of the two procedures. 5. Ability to understand the study protocol and provide written informed consent. 6. A broad set of inclusion criteria was adopted to enroll a patient population that better reflects routine clinical practice. The study aimed to enhance the generalizability of the findings by including patients with various comorbidities, such as preprocedural hypoxemia (room-air SpO₂ ≤ 90%), history of pulmonary surgery, obstructive sleep apnea (OSA), and other pulmonary conditions (including asthma, COPD, chronic bronchitis, emphysema, and pulmonary bullae). Exclusion Criteria: 1. Severe cardiovascular or cerebrovascular diseases. 2. Pregnant patients. 3. History of hypersensitivity to ciprofol. Withdrawal Criteria: 1. Endotracheal intubation required during the procedure. 2. Voluntary withdrawal requested by the patient or their legal representative.
Where it's running
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General hospital of Ningxia medical university, Yinchuan, Ningxia
Yinchuan, Ningxia, China Recruiting
Study contacts
- Study coordinator: Xiaoyong Wei, Degree
- Email: weixy9912@126.com
- Phone: 86-951-674-3252
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.