Study on muscle weakness after surgery in intensive care patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational pilot trial focuses on surgical patients at high risk for intensive care unit admission. Participants will undergo blood and muscle sample collection at specific time points to analyze metabolic, histological, and molecular changes. The study aims to investigate alterations in the blood metabolome associated with intensive care unit acquired weakness (ICUAW) and to identify potential metabolic markers for this condition.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* invasive mechanically ventilated critically ill patient with expected intensive care unit stay \> 3 days
* postoperative patient
* ≥ 18 years old
* American Society of Anesthesiology (ASA) classification ≥ III

Exclusion Criteria:

* moribund patient
* non-curative care (comfort care)

Where it's running

• Medical University of Vienna
  Vienna, State of Vienna, Austria Recruiting
• Klinikum rechts der Isar, School of Medicine, Technical University of Munich
  Munich, Bavaria, Germany Active not recruiting
• Charité - Universitätsmedizin Berlin
  Berlin, State of Berlin, Germany Active not recruiting

Study contacts

• Principal investigator: Stefan J Schaller, MD — Technical University of Munich
• Study coordinator: Stefan J Schaller, MD
• Email: stefan.schaller@meduniwien.ac.at
• Phone: +4314040041020

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Improving walking recovery in patients with muscle weakness from critical illness

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• Understanding muscle recovery in ICU survivors

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• Observing recovery from weakness after severe respiratory and cardiac failure

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  Recruiting Barts & The London NHS Trust · London · NCT03753412

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.