Stigma Healing Inventory: See if a global program can reduce stigma for kids with cancer and their caregivers
Official title: Stigma Healing Inventory Evaluation
Run by St. Jude Children's Research Hospital · NCT07882927 · Data updated 2026-11-12
This study tests a stigma-reduction program for children with cancer and their caregivers to see if it lowers stigma across different cultures.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 8 Years and up |
| Sex | All |
| Enrollment | 2980 (estimated) |
| Sponsor | St. Jude Children's Research Hospital Academic / other |
| Drugs / interventions | chemotherapy, radiation |
| Locations | 1 site (Memphis, Tennessee) |
| Status | Recruiting |
| Started | December 2026 |
| Main results expected | December 2031 |
| Study ends | December 2031 |
| Registry record updated | November 10, 2026 |
| Trial ID | NCT07882927 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 8 to 17.9 years with cancer and their caregivers (18+ for caregivers), who speak Arabic, English, or Spanish, enrolled at St. Jude in Memphis.
✕Probably not a fit
Participants not experiencing meaningful stigma in the assessed domains or those not meeting language criteria may have limited benefit from the intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The study aims to characterize how stigma affects pediatric cancer patients and their caregivers and to develop, adapt, and pilot a stigma-reduction intervention globally. It will enroll about 1,400 patient-caregiver pairs for the characterization phase and a smaller set for the intervention pilot, using the KidsCanShine and CaregiversCanShine tools administered in person or electronically. Participants will be followed for six months with two survey points to assess changes in stigma. Interventions include Pediatric Stigma Education, Pediatric Stigma Standard Education, and an Adapted Stigma Intervention, delivered to eligible children and caregivers who meet language and other criteria. The study is led by St. Jude Children's Research Hospital with no listed collaborators and is implemented at the St. Jude site in Memphis, TN.
Why it matters
Potential benefit: If successful, the program could reduce stigma experienced by children with cancer and their families, improving psychosocial well-being and care experiences.
How similar studies have gone: Prior work with stigma tools in pediatric cancer contexts supports the relevance of structured interventions, though global adaptation is relatively novel for this population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria, AIM 1: * Children with cancer who are actively receiving chemotherapy, radiation, and/or surgery or caregivers of children with cancer actively receiving chemotherapy, radiation, and/or surgery * Ages 8 to 17.9 years (patients); age 18+ (caregivers) * Speaks Arabic, English, or Spanish (St. Jude will enroll English-speakers only). Inclusion Criteria, AIM 3: * Children with cancer who are actively receiving chemotherapy, radiation, and/or surgery or caregivers of children with cancer actively receiving chemotherapy, radiation, and/or surgery * Ages 8 to 17.9 years (patients); age 18+ (caregivers) * Speaks Arabic, English, or Spanish (St. Jude will enroll English-speakers only) * Experienced moderate-high scores in at least 1 domain as assessed by baseline KidsCanSHINE or CaregiversCanSHINE survey assessments. * Specify any clinical (e.g., life expectancy, co-existing disease demographic (e.g., age) or other characteristics that preclude appropriate diagnosis, treatment or follow-up in the trial.
Where it's running
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St. Jude Children's Research Hospital
Memphis, Tennessee, United States Recruiting
Study contacts
- Principal investigator: Dylan Graetz, MD, MPH — St. Jude Children's Research Hospital
- Study coordinator: Dylan Graetz, MD, MPH
- Email: referralinfo@stjude.org
- Phone: 888-226-4343
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.