SPSIP vs ESP Block for Pain After Mastectomy
Official title: Comparison of Serratus Posterior Superior Intercostal Plane Block and Erector Spinae Plane Block in Breast Surgery in Terms of Ease of Application and Patient Comfort
Run by Sakarya University · NCT07561853 · Data updated 2026-11-12
This study tests whether the serratus posterior superior intercostal plane (SPSIP) block or the erector spinae plane (ESP) block provides a more comfortable, easier-to-place pain relief option after mastectomy.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 25 Years to 65 Years |
| Sex | All |
| Enrollment | 64 (estimated) |
| Sponsor | Sakarya University Academic / other |
| Locations | 1 site (Sakarya) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | November 15, 2026 |
| Study ends | December 15, 2026 |
| Registry record updated | September 11, 2026 |
| Trial ID | NCT07561853 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 25–65 undergoing mastectomy, with ASA physical status I–III, without allergy to local anesthetics or opioids or active severe psychiatric disorders.
✕Probably not a fit
Patients with ASA IV, substance abuse history, or contraindications to regional anesthesia may not benefit from these blocks.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial compares two ultrasound-guided fascial plane blocks commonly used for postoperative analgesia in mastectomy patients. It focuses on ease of application and patient comfort during block placement, with secondary observations on block characteristics and analgesic impact. Eligible participants are adults 25–65 years old, female, with ASA I–III status, undergoing mastectomy. The study is conducted at Sakarya University, leveraging routine clinical practice to assess real-world applicability of these blocks. Outcomes may inform anesthesiology practice about which block is simpler to perform and more comfortable for patients during placement.
Why it matters
Potential benefit: If SPSIP or ESP proves superior in ease and comfort, clinicians could choose the more patient-friendly option, potentially speeding recovery and reducing block-related stress.
How similar studies have gone: There is limited comparative data between SPSIP and ESP blocks for mastectomy analgesia, making this a relatively novel assessment.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female Gender * Mastectomy operation * 25-65 years * American Society Anestheosiology Physical Status I-III Exclusion Criteria: * American Society Anestheosiology Physical Status IV * Alcohol or substance abuse * Known allergy to local anesthetics or opioids * Severe psychiatric disorders
Where it's running
-
Sakarya University-Anesthesiology and Reanimation Department
Sakarya, Turkey (Türkiye) Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.