SNRK and vascular aging in adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines the role of SNRK, a cellular energy sensor, in vascular aging by analyzing serum markers and carotid ultrasound findings. Participants aged 18 to 80 undergo blood tests and carotid artery imaging to explore links between SNRK activity, endothelial cell aging, and vascular changes. The goal is to better understand how vascular aging contributes to cardiovascular risk and whether SNRK-related pathways could become targets for future research. No intervention beyond standard imaging and blood tests is planned, and outcomes will focus on associations rather than causal effects. The study is led by Tianjin Medical University General Hospital in Tianjin, China.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Aged 18-80 years, with the capacity to make decisions independently or represented by an authorized legal guardian;
2. Able to provide complete personal information, medical history, and lifestyle history (e.g., smoking and alcohol consumption history);
3. No history of severe cardiovascular disease, and deemed eligible for inclusion by a physician.

Exclusion Criteria:

1. Women who are pregnant or may become pregnant;
2. Patients with a history of neurological disorders, tumors, severe cardiovascular or pulmonary disease, liver failure, kidney failure, or blood disorders;
3. Patients who have undergone carotid stenting, carotid endarterectomy, or other similar procedures, or who have unilateral carotid artery occlusion due to any cause;
4. Patients who have participated in another clinical trial within the past 4 weeks;
5. Individuals deemed unsuitable for this clinical trial by the investigators.

Where it's running

• Tianjin Medical University General Hospital
  Tianjin, Tianjin Municipality, China Recruiting

Study contacts

• Study coordinator: Xintong Ge, M.D.
• Email: xge@tmu.edu.cn
• Phone: 86-022-60362237

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.