GPIIb/IIIa PET/CT Imaging for Thrombi in the Brain and Body
Official title: Glycoprotein IIb/IIIa PET/CT in Various GPIIb/IIIa-Related Disease
Run by Tianjin Medical University · NCT07813559 · Data updated 2026-11-12
This study tests an imaging tracer called 18F/68Ga-GP1 to see if it safely helps identify thrombi in adults who might have them.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Tianjin Medical University Academic / other |
| Locations | 3 sites (Hefei, Anhui and 2 other locations) |
| Status | Recruiting |
| Started | September 1, 2026 |
| Main results expected | September 1, 2031 |
| Study ends | September 1, 2031 |
| Registry record updated | September 10, 2026 |
| Trial ID | NCT07813559 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) with suspected, newly diagnosed, or previously treated thrombi who are scheduled for GPIIb/IIIa PET/CT imaging and can provide informed consent.
✕Probably not a fit
Patients with non-thrombi lesions, pregnancy, or inability to consent may not benefit from this imaging approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates the safety and diagnostic performance of 18F/68Ga-GP1 PET imaging for detecting thrombi in adults. The approach uses a small molecule tracer that targets GPIIb/IIIa receptors to visualize thrombi with PET/CT. Eligible participants may have suspected, newly diagnosed, or previously treated thrombi and are scheduled for GPIIb/IIIa PET/CT imaging. The study is conducted at multiple Chinese centers led by Tianjin Medical University with collaborations at affiliated hospitals. Outcomes focus on safety and how well GP1 PET imaging can detect thrombi compared with standard imaging.
Why it matters
Potential benefit: If successful, GP1 PET imaging could improve the accuracy and speed of thrombus detection, aiding diagnosis and treatment planning.
How similar studies have gone: Other groups are actively developing GPIIb/IIIa PET tracers, but each tracer and setting has limited published validation so far.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * (i) adult patients (aged 18 years or order); (ii) patients with suspected or new diagnosed or previously treated thrombi (supporting evidence may include MRI, CT, tumor markers and pathology report); (iii) patients who had scheduled GPIIb/IIIa PET/CT scan; (iv) patients who were able to provide informed consent (signed by participant, parent or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee. Exclusion Criteria: * (i) patients with non-thrombi lesions; (ii) patients with pregnancy; (iii) the inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.
Where it's running
-
The First Affiliated Hospital of University of Science and Technology of China
Hefei, Anhui, China Recruiting -
The Affiliated Hospital of Qingdao University
Qingdao, Shandong, China Recruiting -
Tianjin Medical University General Hospital
Tianjin, Tianjin Municipality, China Recruiting
Study contacts
- Study coordinator: Haonan Yu, MD
- Email: dreamadam@126.com
- Phone: +8613821000597
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.