Clinical trial Recruiting at 3 sites Observational Ages 18 to 90

GPIIb/IIIa PET/CT Imaging for Thrombi in the Brain and Body

Official title: Glycoprotein IIb/IIIa PET/CT in Various GPIIb/IIIa-Related Disease

Run by Tianjin Medical University · NCT07813559 · Data updated 2026-11-12

This study tests an imaging tracer called 18F/68Ga-GP1 to see if it safely helps identify thrombi in adults who might have them.

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Quick facts

Study typeObservational
Ages18 Years to 90 Years
SexAll
Enrollment500 (estimated)
SponsorTianjin Medical University
Academic / other
Locations3 sites (Hefei, Anhui and 2 other locations)
StatusRecruiting
StartedSeptember 1, 2026
Main results expectedSeptember 1, 2031
Study endsSeptember 1, 2031
Registry record updatedSeptember 10, 2026
Trial IDNCT07813559 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) with suspected, newly diagnosed, or previously treated thrombi who are scheduled for GPIIb/IIIa PET/CT imaging and can provide informed consent.

Probably not a fit

Patients with non-thrombi lesions, pregnancy, or inability to consent may not benefit from this imaging approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates the safety and diagnostic performance of 18F/68Ga-GP1 PET imaging for detecting thrombi in adults. The approach uses a small molecule tracer that targets GPIIb/IIIa receptors to visualize thrombi with PET/CT. Eligible participants may have suspected, newly diagnosed, or previously treated thrombi and are scheduled for GPIIb/IIIa PET/CT imaging. The study is conducted at multiple Chinese centers led by Tianjin Medical University with collaborations at affiliated hospitals. Outcomes focus on safety and how well GP1 PET imaging can detect thrombi compared with standard imaging.

Why it matters

Potential benefit: If successful, GP1 PET imaging could improve the accuracy and speed of thrombus detection, aiding diagnosis and treatment planning.

How similar studies have gone: Other groups are actively developing GPIIb/IIIa PET tracers, but each tracer and setting has limited published validation so far.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* (i) adult patients (aged 18 years or order); (ii) patients with suspected or new diagnosed or previously treated thrombi (supporting evidence may include MRI, CT, tumor markers and pathology report); (iii) patients who had scheduled GPIIb/IIIa PET/CT scan; (iv) patients who were able to provide informed consent (signed by participant, parent or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee.

Exclusion Criteria:

* (i) patients with non-thrombi lesions; (ii) patients with pregnancy; (iii) the inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.

Where it's running

  • The First Affiliated Hospital of University of Science and Technology of China
    Hefei, Anhui, China
    Recruiting
  • The Affiliated Hospital of Qingdao University
    Qingdao, Shandong, China
    Recruiting
  • Tianjin Medical University General Hospital
    Tianjin, Tianjin Municipality, China
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.