18F-AIPF-1026 PET/CT for MAO-A related diseases in adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study evaluates how well 18F-AIPF-1026 PET/CT detects MAO-A-related lesions by measuring uptake with SUVmax and calculating sensitivity, specificity, PPV, NPV, and accuracy. Participants include adults with suspected, newly diagnosed, or previously treated depression or other MAO-A–related conditions who are scheduled for MAO-A PET/CT. The study analyzes PET/CT images to determine diagnostic performance across different lesion types and clinical scenarios. Interventions are diagnostic imaging with 18F-AIPF-1026, and results will inform potential utility for diagnosis and management. The investigation is led by Tianjin Medical University with multiple collaborating centers in China.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- (i) adult patients (aged 18 years or order); (ii) patients with suspected or new diagnosed or previously treated depression (supporting evidence may include MRI, CT, tumor markers and pathology report); (iii) patients who had scheduled MAO-A PET/CT scan; (iv) patients who were able to provide informed consent (signed by participant, parent or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee.

Exclusion Criteria:

\- (i) patients with non-malignant lesions; (ii) patients with pregnancy; (iii) the inability or unwillingness of the research participant, parent or legal representative to provide written informed consent.

Where it's running

• The First Affiliated Hospital of University of Science and Technology of China
  Hefei, Anhui, China Recruiting
• The Affiliated Hospital of Qingdao University
  Qingdao, Shandong, China Recruiting
• Tianjin Medical University General Hospital
  Tianjin, Tianjin Municipality, China Recruiting

Study contacts

• Study coordinator: Ying Wang, MD
• Email: macrossplusvoices@163.com
• Phone: +8618702292537

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.