Single-stage reconstruction for knees with multiple torn ligaments
Official title: Descriptive Study of Multiligamentary Reconstruction of the Knee: Clinical Results and Postoperative Laxity by Dynamic Radiography.
Run by Versailles Hospital · NCT03932838 · Data updated 2026-11-12
This project will compare allograft versus autograft single-stage knee reconstruction to see which leads to better outcomes and less postoperative looseness in adults with multiple ligament injuries.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Versailles Hospital Academic / other |
| Locations | 1 site (Le Chesnay) |
| Status | Recruiting |
| Started | December 1, 2017 |
| Main results expected | December 1, 2019 |
| Study ends | June 1, 2035 |
| Registry record updated | March 17, 2026 |
| Trial ID | NCT03932838 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 who had a one-time single-stage allograft or autograft reconstruction for multiligament knee injury, with no prior surgery on the affected knee and no associated fractures or neurovascular injuries, are ideal candidates.
✕Probably not a fit
Patients with femur or tibia fractures, neurological or vascular injury from the trauma, prior surgery on the affected knee, or ligamentous injury in the contralateral knee are not eligible and would not benefit from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a single-center, interventional clinical comparison of adults (>18) who underwent one-time single-stage reconstruction for multiligament knee injuries using either allograft or autograft tissue. Patients receive clinical and radiologic follow-up, including dynamic radiography to measure postoperative laxity in anterior, posterior, varus and valgus planes. The study excludes cases with associated femur or tibia fractures, neurological or vascular trauma, prior surgery on the affected knee, or ligament injury in the opposite knee. Data will be used to describe clinical outcomes and quantify differences in postoperative laxity between the two graft types.
Why it matters
Potential benefit: If successful, the results could help surgeons choose the graft type that reduces postoperative laxity and improves functional outcomes after multiligament knee reconstruction.
How similar studies have gone: There is little published data; one prior study reported postoperative laxity by dynamic radiography but no prior studies directly compare allograft versus autograft in this setting, so the direct comparison is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients operated for one-time allograft or autograft reconstruction of multiligamentous knee injury * \>18 years old Exclusion Criteria: * Neurological or vascular injury during trauma. * Fracture of the femur or both bones of the leg. * Ligamentous lesion on the contralateral knee. * History of surgery on the affected knee.
Where it's running
-
CH de Versailles
Le Chesnay, France Recruiting
Study contacts
- Study coordinator: Nicolas Pujol
- Email: npujol@ch-versailles.fr
- Phone: 0139639565
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.