Observational registry for COPD patients in ICU

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry focuses on patients with acute exacerbations of Chronic Obstructive Pulmonary Disease (COPD) who are admitted to an Intensive Care Unit (ICU). It aims to document the clinical characteristics, treatment approaches, and outcomes of these patients to better understand the severity and management of COPD exacerbations. By collecting data from multiple centers, the study seeks to highlight the socio-economic impact of COPD and the burden of exacerbations on healthcare systems. The findings may inform future clinical practices and guidelines for managing severe COPD cases.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age ≥ 40 years old
2. COPD documented or strongly suspected

   * Chronic respiratory symptoms (dyspnoea, cough and/or sputum)
   * Exposure to a known risk factor for COPD (such as tobacco smoke)
   * If available, respiratory function tests showing non- or partially reversible obstructive syndrome (post-bronchodilator ratio FEV1/CV \< 0.7)
3. Severe acute exacerbation, defined as a worsening of the patient's usual respiratory symptoms with signs of acute respiratory distress (polypnoea ≥ 30 cycles.min-1 or use of accessory respiratory muscles) and/or hypercapnic acidosis (with PaCO2 ≥ 45 mmHg and pH ≤ 7.35)
4. Admission to an ICU, or a dedicated respiratory intensive care unit

Exclusion Criteria:

1. Known asthma (according to the criteria of the international "Global Initiative for Asthma" guidelines)
2. Patient refusal to participate (information note, application for non-opposition)

Where it's running

• Centre hospitalier de Versailles
  Le Chesnay, France Recruiting

Study contacts

• Principal investigator: Alexis Ferré, MD — Centre hospitalier de Versailles, 78150, Le Chesnay
• Study coordinator: Alexis Ferré, MD
• Email: aferre@ght78sud.fr
• Phone: +33139638700

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.