Serratus Posterior Superior Intercostal Plane Block to Ease Pain After Minimally Invasive Valve Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind, placebo-controlled trial examines the analgesic effect of the serratus posterior superior intercostal plane (SPSIP) block in adults undergoing minimally invasive cardiac valve surgery via mini-thoracotomy. Participants are randomly assigned to receive an ultrasound-guided SPSIP block with either bupivacaine or saline, in addition to standard anesthesia and multimodal analgesia. Blinding is maintained for patients and outcome assessors to ensure unbiased assessment of pain and opioid consumption. The study aims to determine if the local anesthetic SPSIP block reduces postoperative opioid needs and improves pain control compared with placebo.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patients aged 18-75 years
* ASA physical status I-III
* Scheduled for elective minimally invasive cardiac valve surgery via mini-thoracotomy
* Able to understand and use the Numeric Rating Scale (NRS)
* Provided written informed consent

Exclusion Criteria:

* Age \>75 years
* Known allergy or hypersensitivity to local anesthetics (e.g., bupivacaine)
* Coagulopathy or ongoing anticoagulant therapy that cannot be discontinued
* Infection at the planned block site
* Chronic opioid use or chronic pain conditions
* Severe pulmonary disease affecting respiratory assessment
* Neurological or psychiatric disorders interfering with pain assessment
* Emergency surgery
* Pregnancy or breastfeeding
* Refusal to participate

Where it's running

• Fatma Acil
  Diyarbakır, Outside of the US, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Fatma Acil, M.D. — Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
• Study coordinator: Fatma Acil, M.D.
• Email: acilfatma@gmail.com
• Phone: +905337225225

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.