See if LGG helps kids with acute infectious diarrhea

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This multicenter, prospective, randomized trial in Türkiye will compare LGG plus standard care to standard care alone for children with acute infectious diarrhea. Participants are recruited from several hospitals and must have diarrheal symptoms starting within 48 hours. The study includes groups receiving LGG, other probiotics or synbiotics, or standard care, with open-label design. The aim is to determine if LGG can shorten illness duration, reduce dehydration, or lessen hospitalizations. Enrollment considers age ranges and excludes recent probiotic use, recent antibiotics, and certain chronic conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Children aged 1 month to 10 years presenting with acute infectious diarrhea (for S. boulardii group)
* Children aged 2 to 10 years presenting with acute infectious diarrhea (other probiotics or synbiotics groups)
* Onset of diarrhea symptoms within the last 48 hours.
* Parental/legal guardian consent obtained.

Exclusion Criteria:

* Use of any probiotics or biotic formulations within the past 8 weeks.
* Use of antibiotics in the last 8 weeks.
* Presence of chronic diseases (e.g., diabetes, congenital heart disease, immunodeficiencies).
* Previous gastrointestinal surgical procedures.

Where it's running

• Eskisehir Osmangazi University Faculty of Medicine
  Eskişehir, Turkey (Türkiye) Recruiting
• Prof.Dr. Cemil Taşçıoğlu City Hospital
  Istanbul, Turkey (Türkiye) Recruiting
• Sisli Hamidiye Etfal Training and Research Hospital
  Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Ener C Dinleyici
• Email: enercagri@gmail.com
• Phone: 00902222392979

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.