Micro-choice-based approach to fatigue management

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a proof-of-concept study conducted in Switzerland to explore a multimodal micro-choice-based intervention for persistent fatigue across conditions such as post-viral fatigue and Long COVID. The program includes a preparation phase, a four-day intensive group treatment, and a follow-up to support behavior integration. The study aims to determine feasibility, acceptability, and potential quality-of-life benefits, addressing a gap in care for fatigue syndromes in the region. If feasible, the approach could support return to daily and occupational activities and potentially reduce long-term disability and healthcare costs.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- Experiencing persistent fatigue with a significant impact on daily functioning (Chalder Fatigue- Scale bimodal ≥ 4)

Exclusion Criteria:

* Have insufficient proficiency in German to complete study-related questionnaires
* Lack the cognitive capacity to understand study procedures (e.g. due to dementia)
* Present with severe medical conditions that may interfere with participation (e.g., advanced organ failure, uncontrolled inflammatory or autoimmune diseases, or severe psychiatric disorders)
* Have active cancer or are currently undergoing cancer treatment
* Are deemed incompatible with group participation during the preparation phase, based on a team assessment. Reasons for exclusion based on group incompatibility include:

  1. Need for a level of individual therapeutic support that exceeds what can be provided in a group setting; b) Refusal to engage in group-based therapy; c) Personality traits that are considered incompatible with group dynamics; d) Failure to attend the mandatory preparatory webinar (no-show is considered a no-go); e) Other significant reasons as determined by the therapeutic team)

Where it's running

• University Hospital Basel
  Basel, Switzerland Recruiting

Study contacts

• Principal investigator: Katrin Bopp, Dr. — University Hospital, Basel, Switzerland
• Study coordinator: Katrin Bopp, Dr.
• Email: katrin.bopp@usb.ch
• Phone: +41 61 265 50 05

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.