Registry of cardiac arrests in children with congenital heart disease

Pediatric Resuscitation Outcome in Children With Heart Disease

Observational Leipzig Heart Science gGmbH · NCT05373498

This study is collecting information on cardiac arrests in children with congenital heart disease in Germany to see how these events affect their recovery and overall health.

Quick facts

Study typeObservational
Enrollment400 (estimated)
AgesN/A to 18 Years
SexAll
SponsorLeipzig Heart Science gGmbH Academic / other
Locations3 sites (Leipzig, Saxony and 2 other locations)
Trial IDNCT05373498 on ClinicalTrials.gov

What this trial studies

This observational study aims to systematically record in-hospital cardiac arrests in pediatric patients with congenital heart disease in Germany. It will collect data on patient demographics, resuscitation efforts, post-resuscitation care, and neurological outcomes using a web-based registry. The study focuses on understanding the mortality and morbidity associated with cardiac arrests in this vulnerable population, particularly after heart surgery. By analyzing correlations between patient characteristics and outcomes, the study seeks to provide valuable insights into the care of these children.

Who should consider this trial

Good fit: Ideal candidates for this study are children under 18 years old with congenital heart defects or related conditions who experience a cardiac arrest requiring resuscitation.

Not a fit: Patients who have a do-not-resuscitate order or for whom informed consent cannot be obtained will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve understanding of outcomes after cardiac arrest in children with congenital heart disease, potentially leading to better care practices.

How similar studies have performed: While there is limited systematic data on this specific cohort, similar observational studies have shown success in improving outcomes through better data collection and analysis.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* congenital heart defects, congenital heart arrhythmia, familial cardiomyopathies, inflammatory heart diseases
* pediatric resuscitation (chest compressions ≥2min) in hospital or on arrival in hospital
* age \<18 years
* informed consent of the parents or legal representative

Exclusion Criteria:

* absence or withdrawal of informed consent of the parents or legal representative
* do-not-resuscitate-order (DNR)

Where this trial is running

Leipzig, Saxony and 2 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cardiac ArrestCongenital Heart Diseasepediatric resuscitation outcomecongenital heart diseaseneurodevelopmental outcome
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.